Research Keyword: cytokine expression

Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake

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Researchers studied a combination of three medicinal mushroom extracts to see if they work better together than separately. They tested this formula on human immune cells called macrophages and found that the combination was significantly more powerful at boosting immune responses than any single mushroom extract alone. This synergistic effect means the three mushrooms enhance each other’s immune-stimulating properties, suggesting this formula combination could have potential therapeutic benefits for immune support.

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The Effect of Combined Treatment of Psilocybin and Eugenol on Lipopolysaccharide-Induced Brain Inflammation in Mice

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This study tested whether psilocybin (an active compound from magic mushrooms) combined with eugenol (a natural compound from cloves) could reduce brain inflammation in mice. Researchers gave mice a substance that triggers inflammation in the brain and then treated them with these compounds before or after the inflammation started. The combination treatment, especially at a 1:50 ratio of psilocybin to eugenol, significantly reduced multiple inflammatory markers in the brain, suggesting this combination could potentially be helpful for treating brain inflammation-related conditions.

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Effects of Cordyceps militaris solid medium on the growth performance, immunity parameters and intestinal health of broilers

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This research shows that a byproduct from growing Cordyceps militaris mushrooms can be used as a feed additive for chickens. When added at low doses to chicken feed, this mushroom byproduct improved the chickens’ growth, boosted their immune system, and created a healthier gut environment with beneficial bacteria. This offers a natural, non-antibiotic option for improving poultry farming.

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Bachu Mushroom Polysaccharide Alleviates Colonic Injury by Modulating the Gut Microbiota

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Researchers studied a polysaccharide extracted from Bachu mushrooms, a traditional medicinal fungus used in China, to treat inflammatory bowel disease in mice. The polysaccharide reduced inflammation by decreasing harmful inflammatory proteins and increasing beneficial bacteria in the gut. Treatment significantly improved disease symptoms and protected the colon from damage caused by chemical-induced colitis, suggesting this mushroom extract could potentially be developed into a natural treatment for inflammatory bowel disease.

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