Research Keyword: cutaneous infection

Nannizziopsis arthrosporioides infection mimicking ophidiomycosis in ball pythons (Python regius)

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A wild-caught boa snake developed severe skin lesions caused by a fungus called Nannizziopsis arthrosporioides. Within a week, six ball pythons housed nearby developed similar skin infections. Using DNA testing and microscopy, researchers confirmed this was the first documented case of this fungus infecting snakes, demonstrating how quickly fungal infections can spread between animals in shared environments.

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Naganishia albidus Causing Perioral Cutaneous Infection: A Rare Case Easily Misdiagnosed

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A 37-year-old man developed an unusual fungal skin infection around his mouth caused by Naganishia albidus, a rare yeast. He was initially misdiagnosed with eczema and his condition worsened with wrong treatment. Advanced fungal testing techniques helped identify the correct organism, and after six weeks of antifungal medication (both oral and topical), his skin completely cleared. This case shows why doctors need to consider rare fungal infections when skin problems don’t respond to typical treatments.

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Continuous debridement combined with short-term posaconazole therapy for cutaneous mucormycosis caused by Rhizopus oryzae infection secondary to acute myeloid leukemia: a case report

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An 80-year-old patient with acute myeloid leukemia developed a serious fungal skin infection caused by Rhizopus oryzae on his lower leg. Doctors treated the infection by repeatedly cleaning out the infected tissue and giving him an antifungal medication called posaconazole for just one week. Despite the short treatment duration due to cost concerns, the patient’s wound gradually healed over four months through continued surgical care, showing that sometimes focused surgical treatment can be as effective as long-term medication.

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Primary cutaneous mixed infection with Cryptococcus uniguttulatus and Mycobacterium tuberculosis

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A 43-year-old man had persistent facial skin lesions for seven years that initially appeared to be fungal infection caused by Cryptococcus uniguttulatus. Standard antifungal treatments failed to completely cure the condition. Advanced genetic testing revealed the lesions were actually caused by two simultaneous infections: the fungus and tuberculosis bacteria. Once both infections were properly identified and treated with appropriate medications, the skin lesions finally healed.

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Phaeohyphomycosis due to Nigrograna chromolaenae in a cardiac transplant patient

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A 71-year-old heart transplant patient developed a slowly growing bump on his finger caused by a rare fungus called Nigrograna chromolaenae. Doctors initially tried common antifungal medications that didn’t work well, but the patient improved significantly when switched to posaconazole treatment. This is the first documented case of this particular fungus infecting a human, highlighting the importance of accurately identifying fungi to choose the right treatment.

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Primary cutaneous mixed infection with Cryptococcus uniguttulatus and Mycobacterium tuberculosis

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A 43-year-old man had a persistent facial rash that didn’t improve with standard antifungal treatments. Doctors initially found a fungal infection called Cryptococcus uniguttulatus using culture tests. However, advanced molecular testing (DNA sequencing) revealed he also had a tuberculosis infection in the same skin lesion. Once both infections were treated with appropriate medications, the patient’s rash finally improved. This case shows that sometimes people can have multiple infections at the same location and that newer diagnostic methods are important for finding these hidden infections.

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Invasive Cutaneous Mucormycosis in a Patient With Chronic Lymphocytic Leukemia on Obinutuzumab, Idelalisib, and Bruton Tyrosine Kinase Degrader: A Case Report

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A 74-year-old man with leukemia developed a serious fungal infection (mucormycosis) on his ankle while taking cancer-fighting drugs. The infection was diagnosed through tissue biopsy examination rather than standard culture tests. Treatment required both powerful antifungal medications and surgical removal of the infected leg below the knee. The patient recovered successfully after this aggressive treatment approach.

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