Research Keyword: connectome

N,N-dimethyltryptamine effects on connectome harmonics, subjective experience and comparative psychedelic experiences

Researchers studied how DMT, a powerful psychedelic drug, changes brain activity patterns and how these changes relate to what people experience. Using advanced brain imaging and network analysis, they found that DMT shifts brain activity away from large-scale network patterns toward smaller, more diverse patterns. Importantly, these brain changes directly tracked with how intensely participants reported experiencing the drug’s effects moment-to-moment.

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The cellular architecture of memory modules in Drosophila supports stochastic input integration

Scientists created a detailed computer model of a memory-processing neuron in the fruit fly brain to understand how memories are stored and recalled. The study found that the neuron’s design allows it to store many different memories using random connections from input neurons, similar to how a brain might encode multiple learned experiences. This research reveals that memories can be efficiently stored without requiring precise positioning of individual neural connections, suggesting the brain uses flexibility and randomness as computational strategies.

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Hierarchical communities in the larval Drosophila connectome: Links to cellular annotations and network topology

Scientists studying fruit fly larval brains discovered that neurons are organized into nested groups or communities, much like departments within a company. These communities perfectly match what scientists knew about neuron types and their functions. Remarkably, certain interneurons act as hubs connecting these different communities, allowing information to flow between specialized brain regions. This organization reveals that the brain’s wiring reflects both its structure and its function.

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