co-expression networks

Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering

mycolabadmin

Fungi are used in industry to produce medicines, chemicals, and enzymes in large fermentation tanks. However, the way these fungal cells grow and clump together greatly affects how much product they make, but scientists don’t yet fully understand or control this growth. This review discusses new tools like genetic engineering, computer modelling, and special imaging techniques that are helping researchers better understand and control fungal growth patterns to improve industrial production.

Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition

mycolabadmin

Researchers discovered a special type of RNA called circDS-1 that helps a deadly fungus switch between two different forms depending on temperature. This fungus normally grows as a mold in soil but transforms into a yeast when it infects humans at body temperature. The circDS-1 RNA acts like a molecular switch that controls this transformation and helps the fungus cause infection. This discovery reveals that fungi may use hidden genetic elements beyond traditional genes to adapt to their environment.

Research Keyword: co-expression networks

Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering

Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition