Research Keyword: clinical protocol

The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology

This article argues that ketamine therapy is commonly misunderstood as a consciousness-expanding psychedelic when it actually works through a completely different biological mechanism. The real therapeutic benefit comes from the brain’s natural reorganization in the days after treatment, not from the altered states people experience during the session itself. The authors call for medical practitioners to stop emphasizing the dissociative experience and instead focus on helping patients build healthy thought patterns during the recovery period when the brain is most ready to form new connections.

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A clinical protocol for group-based ketamine-assisted therapy in a community of practice: the Roots To Thrive model

The Roots to Thrive ketamine-assisted therapy program is a 12-week group treatment that combines ketamine sessions with weekly group meetings, somatic practices, and emotional support. The program integrates both Western clinical approaches and Indigenous wisdom, treating depression, anxiety, and PTSD in groups of 20-40 participants. Over 750 people have participated with significant improvements in mental health symptoms and life functioning, demonstrating that this group-based approach is both safe and effective.

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