Research Keyword: chromoblastomycosis treatment

Establishment of epidemiological cutoff values for Fonsecaea pedrosoi, the primary etiologic agent of chromoblastomycosis, and eight antifungal medications

Chromoblastomycosis is a serious fungal skin infection caused by a fungus called Fonsecaea pedrosoi, particularly affecting people in tropical regions and those in poverty. Researchers from multiple countries tested 148 samples of this fungus against eight different antifungal medications to determine how well each drug works. They established baseline measurements that doctors can use to determine if a patient’s fungal infection might not respond well to standard treatments, helping guide better treatment decisions.

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Improving treatment of chromoblastomycosis: the potential of COP1T-HA and antimicrobial photodynamic therapy against Fonsecaea monophora in vitro

Chromoblastomycosis is a stubborn skin fungal infection that is difficult to treat with current medications and often comes back after treatment. Researchers tested a new treatment using a special light-activated compound called COP1T-HA combined with blue light, which successfully killed the fungus in laboratory tests. The treatment worked quickly and at low doses, showing promise as a potential new therapy for this challenging infection.

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