Research Keyword: chitinase

Genome Sequence, Comparative Genome Analysis, and Expression Profiling of the Chitinase GH18 Gene Family in Cordyceps javanica Bd01

Scientists sequenced the complete genome of Cordyceps javanica, a fungus used to control pest insects. They discovered that this fungus has an expanded family of 27 chitinase genes (GH18), which are enzymes that help the fungus penetrate insect exoskeletons. These genes show strong evolutionary conservation and stability, making them valuable for developing more effective natural pesticides and understanding how fungal biocontrol agents work.

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The Function of Chitinases CmCH1 and CmCH10 in the Interaction of Coniothyrium minitans and Sclerotinia sclerotiorum

Scientists studied two enzyme genes in a fungus that eats other harmful fungi. When they removed one gene at a time, the fungus still worked fine. But when they removed both genes together, the fungus grew slower and couldn’t attack its target fungus as effectively. This shows that these genes work together as a team to help the fungus do its job as a natural pest control agent.

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Enhanced extracellular production of laccase in Coprinopsis cinerea by silencing chitinase gene

Scientists improved the production of laccase, an enzyme with industrial uses in detoxification and food processing, by genetically engineering mushroom cells to have stronger cell walls. By reducing the activity of genes that break down chitin in the cell wall, they created mushroom strains that could better withstand the stirring forces during fermentation, resulting in over twice as much enzyme production. This breakthrough could lead to cheaper, more efficient production of this useful green catalyst on an industrial scale.

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Nitric Oxide-Mediated Regulation of Chitinase Activity and Cadmium Sequestration in the Response of Schizophyllum commune to Cadmium Stress

A culinary mushroom called Schizophyllum commune can be harmed by cadmium pollution. When exposed to cadmium, the fungus produces nitric oxide, which causes enzymes called chitinases to become more active. These active enzymes break down the mushroom’s cell wall, allowing more cadmium to accumulate and ultimately damage the fungus’s growth. By reducing nitric oxide levels, scientists may be able to protect this mushroom from cadmium poisoning.

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