Research Keyword: Chitin Synthase

Analysis of the chitin synthase gene family in Ganoderma lucidum: its structure, phylogeny, and expression patterns

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Scientists studied eight chitin synthase genes in Ganoderma lucidum (reishi mushroom), which are important for building the fungal cell wall and controlling growth. They found that different genes are active at different stages of mushroom development and that six of these genes become more active when exposed to high temperatures, suggesting they help the mushroom survive heat stress. This research helps us understand how mushrooms grow and develop, which could lead to better cultivation methods.

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In vitro activity of seven antifungal agents against Fusarium oxysporum and expression of related regulatory genes

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Researchers tested seven different antifungal medications to find the best treatment for a fungal disease that damages corn crops. Epoxiconazole worked best as a single treatment, but combining pyraclostrobin and difenoconazole together was even more effective. These medications work by interfering with the fungus’s ability to survive and infect corn, making them promising options for protecting corn crops.

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In vitro and In silico investigation deciphering novel antifungal activity of endophyte Bacillus velezensis CBMB205 against Fusarium oxysporum

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Researchers isolated a beneficial bacteria called Bacillus velezensis from medicinal plants that can fight against a dangerous fungus causing banana wilt disease. Through laboratory and computer studies, they identified two natural compounds produced by this bacteria that stop the fungus from growing by damaging its cell walls. This discovery offers a promising eco-friendly alternative to chemical fungicides for protecting banana crops worldwide.

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Cell walls of filamentous fungi – challenges and opportunities for biotechnology

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Filamentous fungi like Aspergillus and Trichoderma are workhorses of the biotechnology industry, producing enzymes and pharmaceuticals worth billions annually. The cell wall surrounding these fungal cells acts as both a barrier and a filter, affecting how well proteins can be secreted into the fermentation medium. By genetically modifying cell wall components, scientists can improve enzyme production efficiency. Additionally, the billions of tons of fungal biomass left over from fermentation contain valuable chitin and chitosan that could be extracted and reused, creating a more sustainable manufacturing process.

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