Research Keyword: cellular homeostasis

Antifungal Effects of the Phloroglucinol Derivative DPPG Against Pathogenic Aspergillus fumigatus

Scientists developed a new antifungal compound called DPPG based on a natural antibacterial molecule produced by soil bacteria. This synthetic derivative showed strong activity against dangerous fungal pathogens like Aspergillus fumigatus and Candida species, which cause serious infections in humans. The compound works by disrupting the fungal cell membrane, causing it to leak and die. Testing in insect models demonstrated effectiveness comparable to current clinical antifungal medications.

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