Research Keyword: cell wall synthesis

Beyond division and morphogenesis: Considering the emerging roles of septins in plasma membrane homeostasis and cell wall integrity in human fungal pathogens

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Septins are protein structures inside fungal cells that help them divide and maintain their outer layers. This review explains how these proteins play crucial roles in fungal infections by helping pathogens survive stress conditions and respond to host defenses. By understanding how septins work, scientists might develop new antifungal medications that target these proteins to fight stubborn fungal infections.

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Healthcare-associated fungal infections and emerging pathogens during the COVID-19 pandemic

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During the COVID-19 pandemic, fungal infections became a serious complication in hospitalized patients, especially those receiving steroids and other immune-suppressing treatments. Common fungal pathogens like Candida and Aspergillus caused dangerous coinfections, with infection rates varying significantly by region. Current antifungal medications have significant limitations including toxicity and resistance, highlighting the urgent need for new and safer antifungal treatments.

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Functions of the Three Common Fungal Extracellular Membrane (CFEM) Domain-Containing Genes of Arthrobotrys flagrans in the Process of Nematode Trapping

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Researchers studied a special fungus called Arthrobotrys flagrans that traps and kills parasitic worms. They focused on three genes (AfCFEM1-3) that produce proteins important for making the sticky traps. When they removed two of these genes, the fungus became better at killing worms, while removing the third gene made it worse. The study shows these genes are crucial for the fungus to create effective sticky traps and could help develop better natural pest control products.

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