cell viability – mycolab.ai

Mathematical Modeling of Escherichia coli and Lactobacillus acidophilus Growth Based on Experimental Mixed Batch Cultivation

mycolabadmin

Researchers studied how two common bacteria – beneficial Lactobacillus acidophilus and harmful E. coli – interact when grown together in laboratory cultures. Using advanced flow cytometry techniques and computer models that track individual bacterial generations, they found that L. acidophilus naturally inhibits E. coli growth through production of lactic acid and antimicrobial compounds. This research provides insights useful for developing probiotic treatments and understanding food fermentation processes.

From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

mycolabadmin

Researchers studied a medicinal mushroom called Ganoderma lucidum to identify compounds that could fight cancer. They found nine rare compounds called depsidones that showed promise against different types of cancer cells, including liver, colon, breast, and lung cancer. The compounds were shown to work by binding to cancer-related proteins, suggesting they could be developed into new cancer treatments.

Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity

mycolabadmin

Researchers tested a medicinal mushroom extract (Reishi/Ganoderma lucidum) to see if it could fight cancer and bacterial infections. The extract showed promising results, being particularly effective against blood cancer and breast cancer cells while being less toxic to normal healthy cells. It also killed bacteria better than some standard antibiotics, suggesting it could potentially be developed into a new type of medicine for treating cancer and infections.

Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

mycolabadmin

This study examined how two medicinal mushrooms, lion’s mane and Reishi, affect nerve cells in the brain. The researchers found that metabolites from these mushrooms don’t harm brain cells and actually boost protective proteins that support cell health and survival. The mushrooms appear to work through a cellular receptor called AhR, which helps facilitate communication between the gut and the brain. These findings suggest that these mushrooms may help support brain function and protect against neurological problems.

Evaluation of Bioactive Compounds, Antioxidant Activity, and Anticancer Potential of Wild Ganoderma lucidum Extracts from High-Altitude Regions of Nepal

mycolabadmin

Researchers studied a medicinal mushroom called Ganoderma lucidum (Reishi) collected from high mountains in Nepal to understand its health benefits. They tested different ways to extract beneficial compounds from the mushroom and found that using ethanol was most effective. The extracts showed strong cancer-fighting properties against cervical cancer cells and powerful antioxidant effects that may help protect the body from damage. These findings suggest this Himalayan mushroom has real therapeutic potential for treating cancer and other diseases.

Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes

mycolabadmin

Researchers tested whether magic mushrooms containing psilocybin could be safely used by people with heart failure, especially those dealing with depression. Using laboratory rat heart cells, they found that extracts from Psilocybe cubensis and Panaeolus cyanescens mushrooms actually protected heart cells from damage and reduced harmful inflammation. The mushroom extracts worked similarly to standard heart medications at the tested concentrations, suggesting they may be safe for use under controlled medical supervision.

The Impact of Psilocybin on High Glucose/Lipid-Induced Changes in INS-1 Cell Viability and Dedifferentiation

mycolabadmin

Researchers tested whether psilocybin, a compound from magic mushrooms, could protect pancreatic β-cells (which produce insulin) from damage caused by high glucose and fat levels. Using laboratory cells, they found that psilocybin reduced β-cell death by preventing apoptosis and showed promise in reducing dedifferentiation (when cells lose their specialized functions). However, psilocybin didn’t restore the cells’ ability to respond to glucose by releasing insulin.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

mycolabadmin

Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Isolation, identification, and production optimization of natural functional pigments produced by Talaromyces atroroseus LWT-1

mycolabadmin

Researchers isolated a special fungus called Talaromyces atroroseus that produces natural red pigments with cancer-fighting properties. These pigments killed cancer cells in laboratory tests while actually helping normal cells grow, which is an ideal combination for therapeutic potential. By optimizing growing conditions, scientists found they can produce large quantities of these pigments efficiently, offering a safe, natural alternative to synthetic dyes for food and cosmetic products.

Synthesis of silver nanoparticles using Eucommia ulmoides extract and their potential biological function in cosmetics

mycolabadmin

Scientists created tiny silver particles using a Chinese medicinal plant extract and found they could help skin look lighter and younger. These particles work by reducing dark pigments and protecting skin from oxidative damage. The nanoparticles were safe at low doses and didn’t harm skin cells, making them promising for use in cosmetic products.

Research Keyword: cell viability