Research Keyword: cell surface hydrophobicity

Microsclerotia formation of the biocontrol fungus Cordyceps javanica IF-1106 and evaluation of its stress tolerance and pathogenicity

Researchers studied a fungus called Cordyceps javanica that can be used to control harmful soil nematodes that damage crop roots. The fungus produces special dormant structures called microsclerotia that can survive extreme heat and UV radiation for extended periods. These microsclerotia showed excellent effectiveness at controlling root-knot nematodes on cucumber plants while also promoting plant growth, making them a promising natural alternative to chemical pesticides.

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Candida albicans Goliath cells pioneer biofilm formation

Researchers discovered that Candida albicans produces giant-sized cells called Goliath cells when zinc is scarce. These oversized cells are extremely sticky and can cling to plastic surfaces like catheters even when exposed to blood flow. Once attached, they form thicker, more resilient biofilms that can seed infections into the bloodstream, making Goliath cells particularly dangerous in hospital settings where catheters are commonly used.

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Candida albicans Goliath cells pioneer biofilm formation

When Candida albicans fungi run out of zinc, they transform into larger cells called ‘Goliath cells’ that are exceptionally sticky to plastic surfaces. Scientists found that these Goliath cells are much better at sticking to catheters and other medical devices than regular yeast cells, even when blood is flowing past them. This discovery helps explain why fungal infections on catheters are so common and could lead to better ways to prevent these dangerous infections that affect hospitalized patients.

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