Research Keyword: Cell cycle arrest

Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

Ganoderma lucidum, a mushroom used in traditional medicine for thousands of years, shows promise in fighting certain blood cancers like leukemia and lymphoma. The mushroom contains special compounds that can kill cancer cells in multiple ways—by triggering cancer cell death, boosting the immune system, and preventing cancer cell growth. While laboratory studies are very encouraging, more testing in humans is needed before it can be used as a standard cancer treatment.

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Clinically proven natural products against breast cancer, with mechanistic insights

This comprehensive review examines ten natural products that have been proven in clinical studies to help fight breast cancer. These products—including omega-3 fatty acids from fish, compounds in broccoli sprouts, garlic, soy, curcumin from turmeric, and green tea—work by triggering cancer cells to self-destruct, stopping their growth, and preventing blood vessel formation that feeds tumors. What makes these findings especially promising is that these natural products appear to work well alongside conventional treatments while causing minimal side effects, offering patients additional options for managing this serious disease.

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The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy

Oyster mushrooms contain special compounds that may help fight cancer and boost the immune system. These mushrooms have antioxidants and other natural chemicals that can slow cancer cell growth and trigger cancer cells to die. When combined with standard cancer treatments, oyster mushroom supplements might improve quality of life and reduce side effects. More research is needed, but oyster mushrooms show promise as an affordable, natural addition to cancer treatment plans.

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Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

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Evaluation of Anticancer Potential of Ganoderma lucidum on MCF-7 Breast Cancer Cells Through Genetic Transcription of Energy Metabolism

Researchers tested extracts from Ganoderma lucidum (Reishi mushroom) against breast cancer cells in the laboratory. They found that the methanol extract was particularly effective at killing cancer cells while leaving healthy cells relatively unharmed. The mushroom works by disrupting the cancer cells’ metabolism and triggering programmed cell death, making it a promising natural treatment option that could complement conventional cancer therapies.

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Honeybee associated Aspergillus niger AW17 as a source of selective anticancer compounds with cytotoxicity evaluation in human cancer cell lines

Scientists discovered that a fungus found in honeybees can produce compounds that effectively kill cancer cells while leaving healthy cells largely unharmed. The fungus (Aspergillus niger AW17) contains unique bioactive compounds including high levels of oleic acid and a rare compound called pachymic acid. When tested against four types of human cancer cells, the fungal extract was particularly effective against liver and colorectal cancer. This finding suggests that exploring specialized environments like beehives could lead to new cancer treatments with fewer side effects.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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Potential of traditional Chinese medicine in gastrointestinal disorders: Hericium erinaceus in chronic atrophic gastritis

Lion’s Mane mushroom (Hericium erinaceus) shows promise for treating chronic stomach inflammation and preventing gastric cancer. Studies indicate it can reduce stomach pain, improve endoscopic findings, and fight harmful bacteria like H. pylori. Its active compounds work by reducing inflammation, oxidative stress, and promoting cancer cell death, offering a natural complement to conventional treatments.

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