Research Keyword: catheter-related infection

First human case of Eidernor doerrieniae colonization in a peritoneal dialysis catheter: A warning from silent contamination

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A 52-year-old dialysis patient noticed brownish particles inside his peritoneal dialysis catheter. Doctors identified a rare fungus called Eidernor doerrieniae using DNA sequencing, which had never been found in humans before. The catheter was removed and the patient received antifungal medications that successfully eliminated the infection without causing serious complications.

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Detection of Multiple Nosocomial Trichosporon asahii Transmission Events via Microsatellite Typing Assay, South America

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Researchers developed a test to identify different strains of a dangerous fungus called Trichosporon asahii that causes serious infections in hospitals. Using this test on samples from South America, they discovered that multiple patients in different hospitals were infected with genetically identical strains, suggesting the fungus was spreading between patients. This typing method is faster and cheaper than other genetic tests, making it useful for hospitals in countries with limited resources to track and control fungal outbreaks.

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Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient

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A peritoneal dialysis patient contracted a rare fungal infection caused by Arthrocladium tropicale, a mold found in damp environments and associated with ant nests. The infection was diagnosed through microscopy and genetic testing, revealing resistance to one antifungal drug but susceptibility to amphotericin B. Treatment with this antibiotic and removal of the dialysis catheter led to full recovery, highlighting the importance of keeping medical equipment storage areas dry and pest-free.

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Spectrum of Fungal Infections in Continuous Ambulatory Peritoneal Dialysis: A 20-Year Retrospective Study From a Tertiary Care Center

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This study examined fungal infections in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) over 20 years at a major Indian hospital. Researchers identified various fungal species causing peritonitis, with Candida species being most common, but discovered increasingly rare fungi involved in these infections. The study found that proper identification of the specific fungus and testing for drug resistance is crucial for effective treatment, typically involving catheter removal and targeted antifungal medications.

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Geotrichosis Due to Magnusiomyces capitatus: A Severe Emerging Invasive Fungal Disease

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A 71-year-old man with cancer undergoing chemotherapy developed a rare and serious fungal blood infection caused by Magnusiomyces capitatus. Despite treatment with antifungal medications, the infection spread throughout his body and he died 10 days after admission. This case highlights how some fungi can resist common antifungal drugs and the importance of quickly identifying the exact type of fungus causing an infection to choose the right treatment.

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Candida albicans Goliath cells pioneer biofilm formation

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Researchers discovered that Candida albicans produces giant-sized cells called Goliath cells when zinc is scarce. These oversized cells are extremely sticky and can cling to plastic surfaces like catheters even when exposed to blood flow. Once attached, they form thicker, more resilient biofilms that can seed infections into the bloodstream, making Goliath cells particularly dangerous in hospital settings where catheters are commonly used.

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