Research Keyword: catalytic mechanism

Exo- and Endo-1,5-α-L-Arabinanases and Prebiotic Arabino-Oligosaccharides Production

This review explores arabino-oligosaccharides (AOS), special sugar compounds that act as prebiotics to feed beneficial gut bacteria. Scientists use enzymes called arabinanases to produce these AOS from plant material, particularly from arabinan found in sugar beets. Different types of these enzymes create different AOS products with varying health benefits, making them promising ingredients for functional foods and supplements that support digestive health.

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Fungal Δ9-fatty acid desaturase: a unique enzyme at the core of lipid metabolism in Aspergillus fumigatus and a promising target for the search for antifungal strategies

Certain dangerous fungal infections like aspergillosis are difficult to treat because current antifungal drugs have significant side effects or the fungi are developing resistance. Scientists have discovered that a specific enzyme called Δ9-fatty acid desaturase, which fungi need to make fats for their cell membranes, has a unique structure different from human cells. This structural difference offers a new opportunity to design antifungal drugs that could kill fungi without harming human cells, potentially providing safer and more effective treatments for serious fungal infections.

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