Research Keyword: cancer therapy

Edible mushrooms as emerging biofactories for natural therapeutics and oral biopharmaceutical delivery

Mushrooms are emerging as natural medicine factories that can be genetically engineered to produce medications taken by mouth. Beyond their traditional use as health foods, scientists are now using advanced genetic techniques to program mushrooms to manufacture therapeutic proteins and vaccines. These engineered mushrooms can naturally package and protect these medications as they pass through the stomach, releasing them safely in the intestines for absorption. This approach offers a sustainable, affordable, and cold-chain-independent alternative to conventional injected medications.

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Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

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Green Myco-Synthesis of Zinc Oxide Nanoparticles Using Cortinarius sp.: Hepatoprotective, Antimicrobial, and Antioxidant Potential for Biomedical Applications

Researchers used mushroom extracts to create tiny zinc oxide particles in an environmentally friendly way. These nanoparticles were tested in mice with liver damage and showed significant protective effects. The particles also demonstrated strong abilities to fight bacteria and fungal infections while acting as powerful antioxidants, suggesting potential use in future medical treatments.

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Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review

Lion’s Mane mushroom shows promising benefits for brain health, potentially improving memory and reducing symptoms of anxiety and depression. It may help prevent cancer by triggering cancer cell death and supports digestive health by promoting beneficial gut bacteria. While generally safe, some people experience mild side effects like stomach discomfort or headaches, making it an accessible supplement for overall wellness.

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How Should the Worldwide Knowledge of Traditional Cancer Healing Be Integrated with Herbs and Mushrooms into Modern Molecular Pharmacology?

This comprehensive review explores how traditional healing practices from around the world use plants and mushrooms to treat cancer. The authors examine thousands of plant species and their active compounds that show promise in fighting various types of cancer through multiple mechanisms like stopping cancer cell growth and triggering cell death. The review emphasizes that proper scientific validation, standardization, and safety testing can help integrate these traditional remedies into modern cancer treatment alongside conventional chemotherapy.

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Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

Scientists are combining polysaccharides (natural compounds found in plants and organisms) with tiny gold particles to create better drug delivery systems. These hybrid nanoparticles can transport medicines directly to cancer cells while reducing side effects and improving treatment effectiveness. The review discusses how these gold-polysaccharide combinations can also fight bacteria and viruses, making them useful for various medical applications beyond cancer therapy.

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Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

Certain fungi called pycnidial fungi can create tiny particles called nanoparticles that are useful in medicine, agriculture, and environmental cleanup. These fungi naturally produce chemicals and enzymes that reduce metal ions into nanoparticles, which have antimicrobial and cancer-fighting properties. While this biological approach is more environmentally friendly than chemical methods, scientists still need to solve challenges like making it work at large scales and ensuring the nanoparticles are safe and stable.

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Phytochemicals as promising agents in Axl-targeted cancer treatment

This review examines natural plant compounds that can block Axl, a protein that helps cancer cells survive and spread. Scientists found that compounds from common foods like apples, grapes, green tea, ginger, and chamomile can reduce Axl levels and kill cancer cells. These natural compounds work through different mechanisms and show promise for treating various cancers, including those resistant to standard chemotherapy drugs.

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Mycosynthesis of Metal-Containing Nanoparticles—Synthesis by Ascomycetes and Basidiomycetes and Their Application

Scientists have discovered that common fungi like mushrooms and molds can produce tiny nanoparticles that fight bacteria, kill cancer cells, and speed up chemical reactions. This fungal method is much cheaper, safer, and more environmentally friendly than traditional chemical production methods. The nanoparticles can be used in medical treatments, wound dressings, water purification, and farming as natural fertilizers and pesticides.

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Modern Pro-Health Applications of Medicinal Mushrooms: Insights into the Polyporaceae Family, with a Focus on Cerrena unicolor

This review explores how medicinal mushrooms, particularly Cerrena unicolor, can be used to improve health through functional foods and supplements. The mushroom contains natural compounds with powerful properties including fighting cancer cells, killing harmful bacteria and viruses, and protecting the body from oxidative stress. Research shows these mushrooms could be incorporated into dairy products and other foods to create innovative health-promoting products for consumers.

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