cancer cell lines – mycolab.ai

Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

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Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

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This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

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Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

Potential of Indonesian Herbal as an Anti-Cancer Therapy: A Systemic Review of in vitro Studies

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This review examined eight Indonesian herbal plants that show promise in laboratory studies for fighting various types of cancer. Soursop leaves were the most researched and consistently showed the ability to kill or slow cancer cells in test tubes by triggering natural cell death pathways. The herbs work through bioactive compounds like flavonoids and alkaloids that can interfere with how cancer cells divide and survive. While these results are encouraging, more research is needed to confirm effectiveness in humans.

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro

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Turkey tail mushrooms, used in traditional Chinese medicine for thousands of years, show promise in fighting melanoma skin cancer. Scientists tested mushroom extracts on melanoma cells in the laboratory and found they kill cancer cells through multiple mechanisms, including triggering programmed cell death and activating the immune system. The mushroom extract also reduced cancer cell migration and showed potential to work better when combined with standard chemotherapy drugs like paclitaxel. These findings suggest turkey tail could be a valuable addition to melanoma treatment strategies.

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

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Researchers studied six fungal strains from Arctic driftwood to find cancer-fighting compounds. Using advanced chemical analysis methods, they identified one strain that was particularly good at killing cancer cells in the lab. From this strain, they isolated five related compounds called depsipeptides that showed strong activity against multiple types of cancer cells. This discovery highlights how fungi from extreme environments like the Arctic could be valuable sources for developing new cancer treatments.

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

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Researchers studied fungi collected from Arctic driftwood to find new cancer-fighting compounds. Using advanced chemical analysis tools, they identified six different fungal strains and found that one strain, Acremonium synnematoferum, produced five unique compounds called depsipeptides. These compounds killed cancer cells in laboratory tests, showing promise as potential cancer treatments. This research highlights how extreme Arctic environments can harbor fungi with powerful medicinal properties.

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Researchers compared two types of medicinal fungi (Phylloporia crataegi and Phylloporia fontanesiae) to understand why one is better at fighting cancer. They used advanced techniques to examine the fungi’s chemicals, genes, and proteins, discovering that P. crataegi contains special compounds like trans-cinnamic acid that help kill cancer cells. This study provides important information for developing new cancer treatments from these fungi.

Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Researchers compared two types of medicinal fungi (Phylloporia crataegi and P. fontanesiae) to understand why one is more effective at fighting cancer. Using advanced molecular analysis techniques, they found that P. crataegi contains higher levels of cancer-fighting compounds and activates more genes related to cancer cell death. These findings suggest that these fungi could be promising sources for developing new cancer treatments.

Research Keyword: cancer cell lines