Research Keyword: cancer

Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study

This study shows that when cancer patients use complementary treatments like mushroom supplements, vitamins, and probiotics alongside their cancer medications under doctor supervision, they experience fewer side effects and better quality of life. Almost 93% of patients had no side effects from these supplements, and many reported less fatigue and better overall wellness. The key finding is that patients should work with their medical team rather than self-prescribing these treatments to avoid dangerous interactions.

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Psychedelic Psilocybin-Assisted Therapy Reduces Depressive Symptoms in Adults with Cancer and Depression

Researchers conducted a trial testing psilocybin-assisted therapy in cancer patients with depression. Participants received a single dose of psilocybin combined with therapy sessions. After eight weeks, most patients showed significant improvement in depression symptoms, with many achieving full remission. The treatment was generally safe with only mild side effects, and patients reported feeling more hopeful and better equipped to cope with their cancer diagnosis.

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Exploring the Bioactive Potential of Calostoma insigne, an Endangered Culinary Puffball Mushroom, from Northeastern Thailand

This research investigated a rare, eye-shaped mushroom called Calostoma insigne that grows in Thai rainforests and is eaten by local people. Scientists confirmed traditional beliefs that the mushroom has health benefits, discovering it has antioxidant, anti-cancer, and anti-diabetic properties. The study also determined the best way to grow this mushroom in laboratories, which could help conserve the endangered species while providing a sustainable food and health resource.

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Recognizing the Importance of Public Health Mycology

Fungal infections are becoming a major global health problem, causing millions of cases and deaths each year, especially in people with weakened immune systems. Different types of fungal infections like aspergillosis and candidiasis are becoming harder to treat because fungi are developing resistance to antifungal medications. The editorial emphasizes that better diagnosis, treatment access, and disease tracking are needed worldwide to combat this growing threat.

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Anticancer Activity of Demethylincisterol A3 and Related Incisterol-Type Fungal Products

This review examines a special group of fungal compounds called incisterols, with focus on demethylincisterol A3 (DM-A3), which shows promise as a cancer-fighting agent. DM-A3 works through multiple mechanisms: it blocks cancer cell growth pathways, inhibits specific cancer-promoting proteins, and has anti-inflammatory effects. The compound has shown strong activity against various cancer types in laboratory and animal studies, making it a candidate for further development as a potential cancer therapy.

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Estimated burden of serious mycoses in Poland

This study reveals that Poland has a significant but underreported problem with serious fungal infections affecting thousands of people annually. The most common fungal infections are yeast infections like candidosis, while mold infections like aspergillosis are the most serious in immunocompromised patients. The research shows that current reporting systems severely underestimate the true burden of these infections, highlighting the need for better surveillance and diagnostic practices.

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ELAV/Hu RNA-binding protein family: key regulators in neurological disorders, cancer, and other diseases

ELAV/Hu proteins are molecular machines that control how cells read and use genetic instructions. Found mostly in the brain and nervous system, these proteins help manage which genes get turned on or off, which is crucial for proper brain development and function. When these proteins go wrong, they can contribute to serious diseases like Alzheimer’s, Parkinson’s, cancer, and autism, making them promising targets for new treatments.

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Utilization of Corn Steep Liquor for the Production of Fairy Chemicals by Lepista sordida Mycelia

Researchers found that corn steep liquor, a waste product from corn processing, can be used as an inexpensive ingredient to help grow mushroom mycelia that produce fairy chemicals. Fairy chemicals are special compounds with potential uses in agriculture and cosmetics, but they are very expensive to produce. By using different concentrations of corn steep liquor in growth media, scientists determined optimal conditions for either growing more mycelia or producing more of the beneficial chemicals, making these compounds more affordable for practical use.

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Cryptococcal endophthalmitis in a patient with malignancy: A case report and literature review

A 50-year-old woman with advanced lung cancer developed a rare fungal eye infection caused by Cryptococcus neoformans, resulting in blurred vision. Doctors diagnosed this through eye surgery and fluid analysis, then treated her with strong antifungal medications both injected into the eye and given systemically. After 10 months of treatment, her vision significantly improved, showing that early detection and aggressive antifungal therapy are critical for preventing blindness from this rare infection.

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