calmodulin gene – mycolab.ai

Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

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Researchers in Thailand studied a fungal infection called sporotrichosis that affects both cats and people. They used advanced DNA sequencing technology to identify the specific type of fungus and understand how it’s related to similar fungi found in other parts of the world. They also tested how well common antifungal medications work against these fungi and found that some isolates are becoming harder to treat.

Phylogeny of Aspergillus section Circumdati and inhibition of ochratoxins potential by green synthesised ZnO nanoparticles

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This research studied yellow-colored fungal species that contaminate crops and can produce harmful toxins called ochratoxins. Scientists identified four different species of these fungi and found that tiny zinc oxide particles made from plant extract could reduce toxin production. The study shows promise for using these nanoparticles to protect food and agricultural products from fungal contamination.

Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

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Researchers in Thailand studied a fungal infection called sporotrichosis by using advanced DNA sequencing technology to identify the exact species and understand how different strains are related to each other. They found that while current treatment options work, some strains are becoming resistant to the main drug used (itraconazole). The study shows that a newer, faster DNA sequencing method can be just as reliable as traditional methods for identifying these dangerous fungi and tracking how they spread between cats and humans.

Re-Identification of Aspergillus Subgenus Nidulantes Strains and Description of Three Unrecorded Species From Korea

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Researchers in Korea re-examined 53 fungal samples from the Korean Agricultural Culture Collection to accurately identify Aspergillus species. Using genetic analysis and microscopic examination, they confirmed 14 different species, including three that were new to Korea: A. griseoaurantiacus, A. puulaauensis, and A. sublatus. These findings help scientists better understand which fungal species are present in Korea and their potential impacts on food, air quality, and human health.

Aspergillus latus: A cryptic causative agent of aspergillosis emerging in Japan

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Researchers in Japan discovered that a dangerous fungus called Aspergillus latus, previously unknown in the country, has been causing infections since at least 2013. This fungus is difficult to identify because it looks similar to other related species and is actually a hybrid created from two different Aspergillus species. The study found seven cases of this fungus in clinical samples and discovered that it is resistant to some common antifungal medications, making accurate identification crucial for proper patient treatment.

Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

mycolabadmin

Researchers in Thailand studied a fungal infection called sporotrichosis caused by Sporothrix schenckii, which infects both cats and humans. Using advanced DNA sequencing technology from Oxford Nanopore, they identified and classified 26 fungal samples and tested how well common antifungal medications worked against them. They found that calmodulin gene sequencing was better than the standard ITS test for identifying the fungus species, and that about one-third of the samples showed reduced sensitivity to the main treatment drug, itraconazole.

Dermatophytosis caused by Trichophyton benhamiae in a sea lion. First report

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A 13-year-old sea lion in a marine park developed ringworm-like skin lesions caused by a fungus called Trichophyton benhamiae, marking the first time this fungus has been identified in this species. Scientists identified the fungus using DNA testing and found it was resistant to common antifungal drugs, so they treated it with a combination of oral medication (terbinafine), topical ozonized oil, and a liver-protecting supplement. After three months of treatment, the sea lion’s skin healed completely.

Comparison of the Filamentous Fungi Library v4.0 MALDI Biotyper Platform vs MSI-2 performance for identifying filamentous fungi from liquid cultures

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This study compared two advanced technologies for identifying dangerous fungi in clinical samples. The MALDI Biotyper FFLv4.0 system identified about 96% of fungi correctly when using liquid culture samples, outperforming the MSI-2 database which identified about 78.5%. Both systems had difficulty with certain difficult-to-distinguish species, especially within Aspergillus and Fusarium groups, but performed well with Mucorales fungi. The findings suggest that continuous updating of these fungal identification libraries is essential for improving patient care.

The frequency distribution of Aspergillus section Nigri from clinical and environmental samples in Iran

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Researchers studied black mold species (Aspergillus section Nigri) found in hospitals and the environment across Iran. They identified eight different species and found that certain types like A. welwitschiae were more common in ear infections while A. tubingensis was more prevalent in soil and air. These findings are important because some of these molds cause serious infections in humans and understanding where they live helps doctors predict and treat infections.

Research Keyword: calmodulin gene