Research Keyword: bronchoscopy

Allergic bronchopulmonary mycosis caused by Scedosporium apiospermum: A case report

A 61-year-old woman developed a rare fungal infection in her lungs caused by Scedosporium apiospermum while undergoing cancer treatment. The infection caused persistent cough, mucus plugs in the airways, and high levels of immune cells called eosinophils. Doctors used genetic testing to identify the specific fungus and then treated her with corticosteroids and antifungal medications, which improved her condition significantly.

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Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

This case study describes three diabetic patients in Sri Lanka who developed a serious lung infection caused by a fungus called mucormycosis. The infection caused cavities in the lungs and symptoms like fever, cough, and weight loss. Two patients recovered with antifungal medication (amphotericin B) and surgery, while one patient sadly died despite receiving treatment. The study emphasizes that doctors should consider this infection in diabetic patients with unusual lung symptoms to catch it early.

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Allergic Bronchopulmonary Mycosis Caused by Schizophyllum commune Successfully Treated With Mepolizumab

A 70-year-old man developed a serious lung condition caused by a fungal infection (Schizophyllum commune) that resulted in dangerous mucus buildup and asthma attacks despite standard treatments. When traditional medications failed, doctors tried a newer biologic drug called mepolizumab that targets immune cells causing inflammation. The treatment successfully cleared the mucus, improved breathing, and allowed the patient to stop taking steroid medications while remaining symptom-free for over two years.

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Pulmonary Mucormycosis in Diabetic Patients: A Case Series From a Tertiary Respiratory Center in Sri Lanka

This case study describes three patients with diabetes who developed a serious lung infection caused by a rare fungus called mucormycosis. The infection presented with various symptoms like cough, fever, and weight loss, and was diagnosed using lung tissue samples that showed the characteristic fungal structures. Two patients recovered with prolonged antifungal medication treatment, while one patient unfortunately died despite receiving prompt treatment, highlighting how serious this infection can be.

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Case Report: Liquid-based cytology diagnosis of pulmonary mucormycosis

A 41-year-old man with diabetes developed a serious lung infection caused by mucormycosis, a rare and dangerous fungus. Doctors diagnosed the infection using liquid-based cytology, a technique that examines fluid from the lungs under a microscope, which proved more effective than traditional methods. Treatment with antifungal medications helped stabilize the patient’s condition, and he remained healthy during an eight-month follow-up. This case highlights how advanced diagnostic techniques can help doctors quickly identify and treat severe fungal infections.

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Schizophyllum commune infection following chimeric antigen receptor T-cell therapy in a patient with lymphoma

A 71-year-old woman receiving CAR T-cell therapy for lymphoma developed a rare fungal lung infection caused by Schizophyllum commune six months after treatment. The infection presented similarly to other fungal diseases affecting the lungs and was diagnosed through bronchoscopy and fungal culture despite negative blood antibody tests. Standard antifungal medication (voriconazole) taken by mouth for four months completely resolved the infection, highlighting the need to consider rare fungi in patients receiving advanced cancer immunotherapies.

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An Atypical Presentation of Allergic Bronchopulmonary Aspergillosis

A 57-year-old man without prior lung problems developed a persistent cough and breathing difficulties that didn’t respond to antibiotics. Imaging showed his lung had collapsed and fluid had accumulated around it, raising concerns about cancer. However, bronchoscopy revealed the collapse was caused by thick mucus plugs filled with Aspergillus fungus rather than cancer. After treatment with antifungal medication and steroids, the patient fully recovered with his lung re-expanding and fluid resolving.

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Acute Respiratory Distress Syndrome Due to COVID-19-Associated Pulmonary Aspergillosis with Rare Extensive Tracheobronchial Pseudomembranous Involvement: A Case Report

An 87-year-old man with COVID-19 developed a rare and severe fungal infection in his airways caused by Aspergillus fumigatus. Doctors used a camera tube (bronchoscope) to see thick, yellowish-white membrane-like material coating his entire windpipe and airways, which is an extremely rare complication. Despite starting antifungal medications, his condition rapidly worsened leading to organ failure and death. This case highlights how COVID-19 can leave patients vulnerable to serious secondary fungal infections that require immediate recognition and treatment.

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Life-threatening airway stenosis due to Scedosporium infection during nontuberculous mycobacteria treatment: A case report

A 73-year-old woman with arthritis being treated with immunosuppressive drugs developed a severe fungal airway infection caused by a rare fungus called Scedosporium apiospermum. Her airway became dangerously narrowed, requiring emergency support with an artificial lung machine while doctors inserted a stent to open her airway. After correctly identifying the fungus and treating it with an antifungal medication called voriconazole, she recovered well with complete healing of the infection.

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A case of Blastomyces helicus pneumonia in a dog from a non-endemic region: diagnostic challenges and successful treatment outcome

A dog developed severe pneumonia from an emerging fungal infection called Blastomyces helicus after traveling to Utah and Idaho. Initial blood tests incorrectly suggested a different fungus, but laboratory culture and genetic testing identified the true culprit. The dog was successfully treated with an antifungal medication called itraconazole and made a complete recovery with careful monitoring over 6 months.

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