Breast cancer – mycolab.ai

Clinically proven natural products against breast cancer, with mechanistic insights

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This comprehensive review examines ten natural products that have been proven in clinical studies to help fight breast cancer. These products—including omega-3 fatty acids from fish, compounds in broccoli sprouts, garlic, soy, curcumin from turmeric, and green tea—work by triggering cancer cells to self-destruct, stopping their growth, and preventing blood vessel formation that feeds tumors. What makes these findings especially promising is that these natural products appear to work well alongside conventional treatments while causing minimal side effects, offering patients additional options for managing this serious disease.

From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

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Researchers studied a medicinal mushroom called Ganoderma lucidum to identify compounds that could fight cancer. They found nine rare compounds called depsidones that showed promise against different types of cancer cells, including liver, colon, breast, and lung cancer. The compounds were shown to work by binding to cancer-related proteins, suggesting they could be developed into new cancer treatments.

Research on the Action and Mechanism of Pharmacological Components of Omphalia lapidescens

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Omphalia lapidescens, a medicinal fungus used in traditional Chinese medicine, contains multiple bioactive compounds with promising health benefits. These compounds can fight parasitic infections, inhibit cancer cell growth, reduce inflammation, and provide antioxidant protection. While clinical use shows benefits especially for gastric cancer when combined with chemotherapy, more research is needed to understand how these compounds work and to improve cultivation and production methods.

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

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Researchers discovered five potent anti-cancer compounds from Arctic fungi called Acremonium strains. Using advanced chemical analysis techniques, they identified and tested these cyclic depsipeptides against various cancer cell types. The most active compound showed promising results against breast cancer and melanoma cells with extremely low concentrations needed for effect. These findings suggest Arctic microorganisms could be valuable sources for developing new cancer treatments.

Anti-Xanthine Oxidase 5′-Hydroxyhericenes A–D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol

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Researchers isolated new compounds from Lion’s mane mushroom (Hericium erinaceus) that can inhibit xanthine oxidase, an enzyme linked to breast cancer development. One compound called hericerin showed strong activity against a specific type of breast cancer cell (T47D cells) while being less harmful to normal cells. The study also corrected a misidentification from previous research, confirming that a compound previously thought to have a different structure was actually adenosine. These findings suggest Lion’s mane could be developed into a natural anti-cancer treatment.

Marine-derived Acremonium strain prioritization using untargeted metabolomics approach for the identification of cytotoxic cyclic depsipeptides

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Researchers studied fungi collected from Arctic driftwood to find new cancer-fighting compounds. Using advanced chemical analysis tools, they identified six different fungal strains and found that one strain, Acremonium synnematoferum, produced five unique compounds called depsipeptides. These compounds killed cancer cells in laboratory tests, showing promise as potential cancer treatments. This research highlights how extreme Arctic environments can harbor fungi with powerful medicinal properties.

Taxonomic characterization and cytotoxic potential of Vietnamese Ganoderma ellipsoideum against human breast cancer MCF-7 cells

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Scientists discovered a mushroom species called Ganoderma ellipsoideum in Vietnam that shows promise in fighting breast cancer. When tested on cancer cells in the laboratory, extracts from this mushroom killed cancer cells effectively. Computer modeling showed that compounds from this mushroom fit perfectly into and block proteins that help cancer cells grow and spread. This discovery suggests the mushroom could be a natural source for developing new cancer drugs.

Encapsulation of progesterone in reishi mushroom composite for optimized hormone replacement and targeted anticancer therapy

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Researchers created a new treatment by combining progesterone (a hormone) with reishi mushroom powder to make it work better in the body. The mushroom acts like a protective wrapper that slowly releases the hormone, making it more effective for treating menopausal symptoms and fighting breast cancer cells. The combination also fights harmful bacteria and fungi while remaining stable during storage. This approach combines traditional medicine with modern pharmaceutical science.

Exploring the Anticancer Potential of Coriolus versicolor in Breast Cancer: A Review

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Coriolus versicolor, a medicinal mushroom known as Turkey tail in North America, contains special compounds that show promise in fighting breast cancer. Research shows these compounds can slow cancer cell growth, trigger cancer cell death through multiple pathways, prevent cancer spread, and boost the immune system’s ability to fight tumors. While early results are encouraging and the mushroom appears safe, more research is needed before it can be recommended as a standard breast cancer treatment.

Phallus indusiatus Extracts Promoted MCF-7 Apoptosis Under TNFα-induced Tumor Microenvironment by Attenuating NF-kappaB and Akt Activation

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Bamboo mushroom extracts show promise in helping treat breast cancer by making cancer cells more sensitive to chemotherapy drugs. The mushroom reduces inflammation and blocks protective signals in cancer cells, making them more likely to die. This research suggests bamboo mushroom could be a helpful supplement for breast cancer patients, especially when used alongside standard cancer treatments.

Research Keyword: Breast cancer