Research Keyword: blood glucose control

The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

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Insights into the Mechanisms and Functional Effects of Insoluble Dietary Fiber Modification: A Review

Insoluble dietary fiber is important for digestive health but its rigid structure limits its usefulness in processed foods and medicine. Scientists can modify this fiber using various techniques like heating, pressure, enzymes, and chemicals to make it more effective. When combined properly, these modification strategies can dramatically improve dietary fiber’s ability to lower cholesterol, control blood sugar, and promote beneficial gut bacteria, making it valuable for functional foods and health applications.

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Seagrass Enhalus acoroides extract mitigates obesity and diabetes via GLP-1, PPARγ, SREBP-1c modulation and gut microbiome restoration in diabetic zebrafish

Researchers tested a seagrass extract called Enhalus acoroides on diabetic zebrafish and found it effectively reduced body weight and blood sugar levels, performing as well or better than metformin, a common diabetes medication. The extract worked by activating genes that promote glucose metabolism and reducing genes that promote fat storage. Importantly, the extract also restored healthy gut bacteria balance, which appears to play a key role in its therapeutic effects. These findings suggest that seagrass could be developed into a natural supplement or functional food to help treat obesity and diabetes.

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The Therapeutic Effect and Mechanism of Traditional Chinese Medicine in Type 2 Diabetes Mellitus and Its Complications

Traditional Chinese Medicine uses various herbs and plant compounds to treat Type 2 diabetes by improving how the body controls blood sugar and protects the pancreas. Many common TCM herbs like ginseng, rehmannia, and coptis work through natural mechanisms that reduce inflammation, protect cells from damage, and improve how the body uses insulin. Research shows TCM may also help prevent or reduce diabetes-related complications affecting the eyes, kidneys, and nerves. These herbal treatments offer potential benefits with fewer side effects compared to conventional medications.

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Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice

Researchers created special tablets from two edible mushrooms (yellow oyster mushroom and lion’s mane) enriched with trace elements (chromium, zinc, germanium) to treat diabetes in mice. After three weeks of treatment, the high-dose tablets reduced blood sugar levels by 29%, improved cholesterol levels, boosted the body’s natural antioxidant defenses, and shifted the gut bacteria toward beneficial types that support metabolic health. These results suggest that mushroom-based treatments could potentially offer a natural way to help manage diabetes.

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