Biotransformation – Page 2

Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass

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Researchers enhanced a traditional Peruvian fermented potato food called tocosh by adding selenium-enriched yeast. This combination reduced inflammation markers in immune cells without affecting its blood sugar impact or antioxidant properties. The resulting product shows promise as a functional food that could help people manage inflammatory conditions while improving nutritional content.

Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

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A type of white rot fungus called Trametes hirsuta can effectively remove harmful oestrogen chemicals from water and soil. The fungus produces special enzymes that break down these hormones into less toxic compounds within just one day. This discovery suggests the fungus could be used as a natural treatment to clean up environmental contamination caused by oestrogens from human waste and pharmaceutical use.

Astragalus Shiitake—A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line

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Scientists developed a new type of Shiitake mushroom by growing it on a special substrate enriched with Astragalus root. This novel mushroom contains significantly more beneficial polysaccharides than regular Shiitake. When tested against colorectal cancer cells, extracts from this mushroom showed strong cancer-fighting properties, with the ultrasound extraction method being most effective. This research suggests Astragalus Shiitake could become a powerful functional food for cancer prevention and treatment.

Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

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Scientists discovered that a white rot fungus called Trametes hirsuta can effectively remove harmful oestrogen hormones from water and soil. Within just one day, the fungus eliminated more than 90% of two common oestrogens (E1 and E2) that pollute our environment through pharmaceutical waste and animal farming. The fungus achieves this by producing special enzymes that couple oestrogen molecules together into larger, less harmful compounds that can be easily removed.

Boldenone and Testosterone Production from Phytosterol via One-Pot Cascade Biotransformations

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Scientists developed an efficient biological process to produce testosterone and boldenone (important medical steroids) from plant sterols using two microorganisms working together. The fungus Curvularia converts the intermediate products produced by bacteria into the desired compounds. This green biotechnology approach avoids chemical synthesis and could provide a more sustainable way to produce these widely-used medicines for humans and animals.

Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

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Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

Research Keyword: Biotransformation

Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass

Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

Astragalus Shiitake—A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line

Oestrogen Detoxification Ability of White Rot Fungus Trametes hirsuta LE-BIN 072: Exoproteome and Transformation Product Profiling

Boldenone and Testosterone Production from Phytosterol via One-Pot Cascade Biotransformations

Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential