Research Keyword: bioreactor

Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

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Galacto-Oligosaccharides Exert Bifidogenic Effects at Capsule-Compatible Ultra-Low Doses

This study tested whether tiny doses of a prebiotic called galacto-oligosaccharides (GOS) could be effective when taken in capsule form instead of large sachets. Researchers used a specially designed laboratory system to simulate how these compounds work in the human gut. Even at the lowest dose tested (0.5 g), the GOS successfully increased beneficial gut bacteria and produced helpful compounds that support digestive health, while producing minimal gas.

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Environmental Impacts and Strategies for Bioremediation of Dye-Containing Wastewater

Textile factories release large amounts of dyes into water, creating serious pollution problems. Scientists have discovered that tiny living organisms like bacteria, fungi, and algae can eat and break down these dyes into harmless substances. This biological approach is cheaper, safer, and more environmentally friendly than traditional chemical methods used to clean wastewater, making it a promising solution for industries worldwide.

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Water Quality Assessment and Decolourisation of Contaminated Ex-Mining Lake Water Using Bioreactor Dye-Eating Fungus (BioDeF) System: A Real Case Study

Researchers tested a natural solution for cleaning polluted water from an old mining lake in Malaysia. They used a special fungus called Ganoderma lucidum in a system called BioDeF that acts like a sponge to remove dirt and discoloration from contaminated water. After just 48 hours, this fungus-based system removed over 90% of the water’s brown color, offering a cheap and eco-friendly alternative to traditional water cleaning methods.

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Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering

Fungi are used in industry to produce medicines, chemicals, and enzymes in large fermentation tanks. However, the way these fungal cells grow and clump together greatly affects how much product they make, but scientists don’t yet fully understand or control this growth. This review discusses new tools like genetic engineering, computer modelling, and special imaging techniques that are helping researchers better understand and control fungal growth patterns to improve industrial production.

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The value of microbial bioreactors to meet challenges in the circular bioeconomy

Scientists are using specially designed containers called bioreactors to grow helpful microorganisms and mushrooms that can solve environmental and health problems. These bioreactors can produce medicines like natural diabetes treatments from mushrooms, create eco-friendly plastics, clean up polluted water, and turn waste products into valuable materials. This approach is sustainable, safe, and scalable, supporting the United Nations’ goals for a healthier planet.

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Burst agitation rate promotes sustained semicontinuous cultivation of filamentous fungi in stirred tank reactors

Scientists improved the way shiitake mushrooms are grown in fermentation tanks by using a smart agitation strategy. Instead of constant stirring, they used periodic bursts of high-speed mixing to prevent clumping while maintaining healthy fungal growth. This approach increased the amount of usable biomass produced and allowed the fermentation to run longer without interruption, making mushroom cultivation more efficient and sustainable.

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Edible mycelium as proliferation and differentiation support for anchorage-dependent animal cells in cultivated meat production

Scientists developed a new technology using edible mushroom mycelium (the root-like structure of fungi) as a scaffold to grow animal muscle cells for cultivated meat production. They tested different fungal species and found that mycelium from koji mold (Aspergillus oryzae) worked best for supporting cell growth and maturation. Unlike current plastic microcarriers that must be removed from the final product, these edible carriers can be incorporated directly into the meat, adding nutritional value and reducing waste.

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Cell walls of filamentous fungi – challenges and opportunities for biotechnology

Filamentous fungi like Aspergillus and Trichoderma are workhorses of the biotechnology industry, producing enzymes and pharmaceuticals worth billions annually. The cell wall surrounding these fungal cells acts as both a barrier and a filter, affecting how well proteins can be secreted into the fermentation medium. By genetically modifying cell wall components, scientists can improve enzyme production efficiency. Additionally, the billions of tons of fungal biomass left over from fermentation contain valuable chitin and chitosan that could be extracted and reused, creating a more sustainable manufacturing process.

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Filamentous fungal pellets as versatile platforms for cell immobilization: developments to date and future perspectives

Filamentous fungi, commonly known as molds, can be grown into small spherical structures called pellets that act as excellent platforms for attaching and growing various types of cells. These fungal pellets are sustainable, biodegradable alternatives to synthetic materials and can support different cell types for applications ranging from producing cultivated meat to treating wastewater. The porous structure of fungal pellets allows cells to attach and grow while maintaining the ability to transfer nutrients and oxygen efficiently.

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