Research Keyword: biofilm cultivation

Cunninghamella echinulata DSM1905 biofilm-based L-asparaginase production in pneumatically-driven bioreactors

Scientists tested different types of bioreactors to grow a fungus called Cunninghamella echinulata that produces L-asparaginase, an enzyme used to treat leukemia and lymphoma. They found that a special hybrid bioreactor with a mesh scaffold allowed the fungus to form a biofilm, which produced significantly more of the therapeutic enzyme than other reactor types. This discovery could improve the production of cancer-fighting medications.

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