bioactive metabolites

Isolation and Evaluation of Erinacine A Contents in Mycelia of Hericium erinaceus Strains

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Researchers developed a new method to extract and purify erinacine A, a beneficial compound from lion’s mane mushrooms, using an advanced separation technique called high-speed countercurrent chromatography. They tested 15 different mushroom strains and found that a wild strain called HeG produced significantly more erinacine A than commercially cultivated varieties. Erinacine A shows promise for protecting brain health and potentially helping with diseases like Alzheimer’s and Parkinson’s. This discovery could help make erinacine A supplements more accessible and affordable for consumers.

Special Issue: Marine-Derived Compounds Applied in Cardiovascular Disease

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This collection of studies explores how compounds from ocean sources like seaweed, fish, shrimp, and microalgae can help protect heart health and prevent cardiovascular diseases. Researchers examined various marine ingredients and found they can reduce inflammation, lower cholesterol, reduce blood pressure, and prevent blood clots. The findings suggest that marine-derived products could become safer, more affordable alternatives or complements to current heart disease medications while supporting sustainable ocean resource use.

Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

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Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

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This research examined how Lion’s Mane mushroom extracts made with different liquids can fight infections and oxidative damage. The water-based extract was best at preventing viruses and free radical damage, while the ethyl acetate extract worked best against bacteria and fungi. The study identified 16 beneficial compounds in the mushroom and suggests it could be used as a daily supplement to protect against infections and oxidative stress.

From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

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Researchers studied a medicinal mushroom called Ganoderma lucidum to identify compounds that could fight cancer. They found nine rare compounds called depsidones that showed promise against different types of cancer cells, including liver, colon, breast, and lung cancer. The compounds were shown to work by binding to cancer-related proteins, suggesting they could be developed into new cancer treatments.

Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

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Researchers isolated tiny particles called extracellular vesicles (EVs) from a medicinal mushroom called king oyster mushroom (Pleurotus eryngii). These EVs act like natural delivery packages containing beneficial compounds like antioxidants and anti-inflammatory molecules. The study found that EVs from mushroom mycelium (the root-like part) were purer and more potent than those from the mushroom cap, with strong abilities to neutralize harmful free radicals in the body.

Biodiversity and biological applications of marine actinomycetes—Abu-Qir Bay, Mediterranean Sea, Egypt

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Researchers isolated bacteria called actinomycetes from the Mediterranean Sea in Egypt that naturally produce colorful pigments. They found that one specific bacterium (Streptomyces tunisiensis) produces a green pigment with promising anti-inflammatory properties similar to common pain relievers. By optimizing the growth conditions, the scientists increased pigment production by over 12 times, suggesting potential applications in medicine and industry.

Sea buckthorn bioactive metabolites and their pharmacological potential in digestive diseases

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Sea buckthorn is an ancient medicinal plant containing hundreds of bioactive compounds that show promise in treating digestive diseases like stomach ulcers, colitis, and liver problems. This comprehensive review of 85 scientific studies found that sea buckthorn’s active ingredients work through multiple mechanisms including reducing inflammation, fighting harmful bacteria, protecting the intestinal lining, and balancing gut bacteria. The research suggests sea buckthorn could become a valuable natural supplement for digestive health, though more clinical trials are needed to confirm optimal doses and long-term effectiveness in humans.

The Effect of Supplementing Mushroom Growing Substrates on the Bioactive Compounds, Antimicrobial Activity, and Antioxidant Activity of Pleurotus ostreatus

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This study investigated how adding wheat bran to mushroom growing substrates affects oyster mushroom quality and medicinal properties. The researchers found that wheat bran supplementation increased mushroom yield but slightly decreased antioxidant power, while the mushrooms produced antimicrobial compounds effective against various bacteria and fungi. The mushrooms contained beneficial compounds like vitamin E and phenols, suggesting they could be developed as natural alternatives to synthetic antibiotics.

Winning the battle of intestinal peace with Bacillus—a multifaceted approach to animal health, immunity, and future applications in monogastric livestock production

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This review examines how Bacillus bacteria, when added to animal feed, can improve the health and growth of chickens and pigs. These bacteria work by producing beneficial compounds that strengthen the gut, improve digestion, reduce harmful bacteria, and boost the immune system. Bacillus probiotics offer a natural alternative to antibiotics, helping reduce antibiotic resistance while keeping animals healthier and more productive.

Research Keyword: bioactive metabolites