Research Keyword: bioactive compounds

Genome-Mining Based Discovery of Pyrrolomycin K and L from the Termite-Associated Micromonospora sp. RB23

Researchers discovered two new antimicrobial compounds called pyrrolomycins from a bacterium found in termite guts using genome analysis and advanced chemistry techniques. These compounds are modified versions of known antimicrobial molecules, featuring halogenated structures. Interestingly, the bacteria appears to protect itself from its own toxic compounds through chemical modifications, a strategy that researchers believe could inform the design of new antibiotics to combat drug-resistant bacteria.

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Green Valorization Strategies of Pleurotus ostreatus and Its By-Products: A Critical Review of Emerging Technologies and Sustainable Applications

Oyster mushrooms generate large amounts of agricultural waste including stems, leftover plant material, and spent growing substrate. These waste products contain many healthy compounds like fiber, β-glucans, and antioxidants that are usually thrown away. Scientists are developing new extraction technologies using ultrasound, microwaves, and other methods to recover these beneficial compounds from mushroom waste for use in functional foods like meat products, baked goods, and dairy items, reducing waste while creating healthier food ingredients.

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Mushroom Bioactive Molecules as Anticancerous Agents: An Overview

Mushrooms contain natural compounds that show promise in fighting cancer by triggering cancer cell death and boosting immune function. Different mushroom species like oyster, shiitake, and button mushrooms contain substances such as beta-glucans and other polysaccharides that have demonstrated anticancer properties in laboratory and animal studies. While these mushroom compounds work through multiple mechanisms including preventing new blood vessel formation to tumors and stopping cancer cell division, more human clinical trials are needed to confirm their effectiveness as cancer treatments.

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Microbial communities inhabiting the surface and gleba of white (Tuber magnatum) and black (Tuber macrosporum) truffles from Russia

This research identifies the various microorganisms living inside truffles, particularly Tuber magnatum (white truffle) and Tuber macrosporum (black truffle). The study found that a yeast-like fungus called Geotrichum consistently lives in both truffle types and likely helps with spore dispersal through smell-producing compounds. The researchers discovered that different parts of the truffle have different microbial communities, which explains why truffles have such unique flavors and aromas.

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