bioactive compounds – Page 15

High Efficiency In Vitro Wound Healing of Dictyophora indusiata Extracts via Anti-Inflammatory and Collagen Stimulating (MMP-2 Inhibition) Mechanisms

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This study examines bamboo mushroom extracts for their ability to promote skin wound healing. Researchers tested three different parts of immature bamboo mushrooms and found that the core extract was particularly effective at reducing inflammation and preventing excessive collagen breakdown, which helps wounds heal properly without excessive scarring. The extract performed as well as or better than standard pharmaceutical agents, suggesting it could be a promising natural ingredient for wound healing products.

Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

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This study examined how oyster mushrooms change nutritionally and chemically as they mature from young to fully grown. Researchers found that while mature mushrooms have more overall nutrients and starch-like compounds, younger middle-stage mushrooms have higher levels of beneficial antioxidant compounds and special substances that may help manage blood sugar. The findings suggest that when and how you harvest mushrooms matters for what health benefits they provide, helping farmers and food makers decide when to pick mushrooms based on what they want to produce.

Cell walls of filamentous fungi – challenges and opportunities for biotechnology

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Filamentous fungi like Aspergillus and Trichoderma are workhorses of the biotechnology industry, producing enzymes and pharmaceuticals worth billions annually. The cell wall surrounding these fungal cells acts as both a barrier and a filter, affecting how well proteins can be secreted into the fermentation medium. By genetically modifying cell wall components, scientists can improve enzyme production efficiency. Additionally, the billions of tons of fungal biomass left over from fermentation contain valuable chitin and chitosan that could be extracted and reused, creating a more sustainable manufacturing process.

Corrigendum: Compounds purified from edible fungi fight against chronic inflammation through oxidative stress regulation

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This article is a correction to a previous study about beneficial compounds found in edible mushrooms. The study examined how various mushroom-derived substances like polysaccharides and peptides can combat chronic inflammation by reducing oxidative stress in the body. Multiple mushroom species were analyzed for their antioxidant properties and mechanisms of action. The corrections ensure proper citation of the original research sources while maintaining the core scientific findings.

Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages

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This study analyzed the chemical composition of Scorias spongiosa, an edible fungus, at different stages of growth using advanced laboratory techniques. Researchers found that the fungus contains beneficial compounds with antioxidant, anti-inflammatory, and other health-promoting properties. The study recommends harvesting the fungus at its earliest growth stage to preserve the most beneficial compounds for food and nutritional products.

Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

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Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

Interplay of precision therapeutics and MD study: Calocybe indica’s potentials against cervical cancer and its interaction with VEGF via octadecanoic acid

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Researchers discovered that an extract from the Calocybe indica mushroom effectively kills cervical cancer cells while leaving healthy immune cells unharmed. Using computer simulations, they identified that a compound in this mushroom called octadecanoic acid strongly binds to and blocks VEGF, a protein that helps cancer cells grow and spread. The extract reduced cancer cell movement by 50% and prevented cancer cells from forming colonies, suggesting this mushroom could become a new treatment option for cervical cancer.

Mushrooms Do Produce Flavonoids: Metabolite Profiling and Transcriptome Analysis of Flavonoid Synthesis in the Medicinal Mushroom Sanghuangporus baumii

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Researchers discovered that the medicinal mushroom Sanghuangporus baumii produces 81 different flavonoids, compounds known for their health benefits including antioxidant and anti-cancer properties. Using advanced genetic and chemical analysis, they identified the genes and processes responsible for this flavonoid production in mushrooms, which differs from how plants make these compounds. By increasing the activity of a key gene called PAL, they were able to boost flavonoid production in the mushroom. This discovery opens new possibilities for using mushrooms as biological factories to produce flavonoids for medical and nutritional applications.

Endophytic Fungi Isolated from the Brown Alga Sargassum thunbergii in Coastal Korea

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Researchers isolated six previously unknown fungal species living inside the brown seaweed Sargassum thunbergii collected from Korean coastal waters. These fungi, identified through genetic analysis and physical characteristics, belong to families known for producing compounds with antimicrobial and anti-inflammatory properties. The discovery reveals that seaweeds harbor a diverse community of fungi that could potentially be used to develop new medicines and agricultural products.

The rise of Stropharia rugosoannulata industry in China: current state and prospects

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The wine-cap mushroom (Stropharia rugosoannulata) is becoming a major agricultural industry in China with over 494,000 tons produced annually. This large, meaty mushroom is rich in proteins, minerals, and healing compounds that may help fight diabetes, obesity, and heart disease. It grows easily on agricultural waste materials, making it an environmentally friendly crop that’s being used to help rural communities and reduce farming pollution.

Research Keyword: bioactive compounds