Research Keyword: ayahuasca

Reporting of psychotherapeutic methods in psychedelic treatments: on the road to ethical, professional and regulatory oversight

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Researchers reviewed 45 studies on how psychedelic drugs like psilocybin, MDMA, and LSD are used to treat mental health conditions. They found that scientists were not describing the psychological counseling that accompanies these treatments in a consistent or detailed way, making it hard to understand how treatments really work. The study calls for better documentation standards so that treatments can be properly regulated, replicated, and made safer for patients.

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Comparative oral monotherapy of psilocybin, lysergic acid diethylamide, 3,4-methylenedioxymethamphetamine, ayahuasca, and escitalopram for depressive symptoms: systematic review and Bayesian network meta-analysis

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This study compared psychedelic drugs (psilocybin, LSD, MDMA, ayahuasca) with the antidepressant escitalopram for treating depression. Researchers analyzed 19 clinical trials and found that while psilocybin showed promise, its actual effectiveness was smaller than previously reported due to blinding issues in earlier studies. High-dose psilocybin performed better than escitalopram in some comparisons, but had a similar small effect size to current antidepressants.

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Ayahuasca enhances the formation of hippocampal-dependent episodic memory without impacting false memory susceptibility in experienced ayahuasca users: An observational study

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Researchers studied how ayahuasca affects memory in experienced Santo Daime church members who use it regularly. Surprisingly, instead of impairing memory like other psychedelics typically do, ayahuasca enhanced people’s ability to remember details of events they witnessed. Importantly, the drug did not make people more susceptible to false memories or memory distortions, even though the entire study occurred while participants were under its acute effects.

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Corrigendum: Ayahuasca-induced personal death experiences: prevalence, characteristics, and impact on attitudes toward death, life, and the environment

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This article corrects errors in a research study about ayahuasca, a traditional plant medicine. The study examined how experiences with ayahuasca that involve confronting death affect people’s attitudes about mortality, the environment, and life fulfillment. The corrections clarify how often participants used ayahuasca and adjust how the data was visualized in graphs, but the main findings about ayahuasca’s effects remain unchanged.

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