Research Keyword: Aspergillus

Prevalence of toxigenic fungi and mycotoxins in Arabic coffee (Coffea arabica): Protective role of traditional coffee roasting, brewing and bacterial volatiles

This study examined toxin-producing fungi and harmful mycotoxins found in coffee sold in Qatar markets. Researchers tested whether traditional coffee roasting and brewing methods reduce these harmful compounds, and also tested a beneficial bacterium that produces antifungal compounds. They found that higher roasting temperatures and brewing significantly reduced the dangerous toxins, and the bacterial volatiles completely stopped fungal growth on coffee beans, offering a natural alternative to chemical fungicides.

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Assessing the Validity and Impact of Remote Digital Image Reading in Fungal Diagnostics

This study tested whether trained mycologists could accurately identify fungal infections from digital images viewed remotely, similar to how radiologists review X-rays. Five experienced laboratory professionals analyzed 474 images of different fungi with accuracy rates between 78-93%. The results suggest that remote digital diagnosis could help hospitals in developing countries where expert mycologists are scarce, enabling faster and more accurate diagnosis of serious fungal infections.

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Clinical and Genomic Insights into Antifungal Resistance in Aspergillus Isolates from Thailand

Researchers in Thailand identified a dangerous fungal infection caused by Aspergillus fumigatus that is resistant to azole antifungal drugs. This is the first time this specific drug-resistant strain has been found in a patient sample in Thailand, though it had been previously detected in environmental samples. The study used genetic testing to understand how the fungus developed resistance and found that it has altered genes that help it survive the antifungal medications commonly used to treat infections.

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mGem: How many fungal secondary metabolites are produced by filamentous fungi? Conservatively, at least 1.4 million

Scientists have discovered about 30,000 fungal compounds with useful properties, from life-saving antibiotics like penicillin to cholesterol-lowering drugs. However, new research suggests that fungi actually produce somewhere between 1.4 million and 4.3 million different chemical compounds, meaning we’ve only discovered about 1-2% of what’s out there. By studying the genomes of fungi, researchers estimate that for every fungal medicine we know about, there could be 50-100 more waiting to be discovered, representing an enormous opportunity for developing new drugs and therapies.

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Editorial: Aspergillus-Derived Mycotoxins in the Feed and Food Chain

Aspergillus fungi produce harmful toxins called mycotoxins that can contaminate our food and animal feed at various stages from farm to table. Climate change is making this problem worse by helping these fungi spread and produce more toxins. Scientists are working on multiple solutions including using harmless fungi strains to compete with the harmful ones, using natural plant compounds to stop toxin production, and developing better ways to detect and remove these toxins from food and feed.

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Effect of Rare, Locally Isolated Entomopathogenic Fungi on the Survival of Bactrocera oleae Pupae in Laboratory Soil Conditions

This study tested different types of beneficial fungi to control olive fruit flies, which are major pests in Mediterranean olive groves. Researchers found that several fungi species, particularly those from the Aspergillus genus, can effectively kill olive fly pupae when applied to soil. The results suggest these fungi could be developed into biological pesticides to protect olive crops without harmful chemical insecticides.

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Inhibitive effect of Urginea epigea methanolic extract and silver/zinc oxide nanoparticles on Aspergillus and aflatoxin production

Researchers tested whether a plant called Urginea epigea could stop the growth of a dangerous fungus (Aspergillus flavus) that produces aflatoxins, which can harm humans and animals. The plant extract completely stopped fungus growth at high concentrations and significantly reduced the production of toxins by turning off the genes responsible for toxin production. This suggests that plant-based treatments could offer a natural alternative to synthetic chemical fungicides for protecting food from contamination.

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Optimized Protocol for RNA Isolation from Penicillium spp. and Aspergillus fumigatus Strains

Scientists developed an improved method for extracting RNA from common mold fungi like Penicillium and Aspergillus. The study compared two extraction techniques and found that using a mechanical bead-beater device combined with a chemical solvent called chloroform produced the best results. This optimized method yields high-quality RNA suitable for studying gene expression in these fungi and can be easily used in regular laboratory settings.

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Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

Researchers studied fungi living in sand and water along Persian Gulf beaches to understand potential health risks for swimmers. They found that fungal species, particularly Aspergillus terreus, were abundant in beach sand, with some fungi showing resistance to common antifungal medicines. The study suggests beaches need better monitoring and sanitation practices to protect public health, especially during busy bathing seasons when many visitors enjoy the coast.

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Modeling of mold inactivation via cold atmospheric plasma (CAP)

This research develops a mathematical model to predict how cold atmospheric plasma kills mold, which is important because molds produce toxins that harm human and animal health and damage food and buildings. The model uses equations to describe mold growth and plasma effects, allowing researchers to predict outcomes in minutes rather than waiting weeks for lab experiments. The study found that plasma is most effective when its killing power matches the mold’s natural growth rate, causing complete extinction.

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