Research Keyword: antiviral therapy

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

This research examined how Lion’s Mane mushroom extracts made with different liquids can fight infections and oxidative damage. The water-based extract was best at preventing viruses and free radical damage, while the ethyl acetate extract worked best against bacteria and fungi. The study identified 16 beneficial compounds in the mushroom and suggests it could be used as a daily supplement to protect against infections and oxidative stress.

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Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

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Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

Scientists are searching for new treatments for COVID-19 by studying indole-containing compounds, which are found in many plants and can be made in laboratories. Some approved drugs with indole structures, like the antiviral drug Arbidol, have been repurposed to fight COVID-19. Researchers are also designing new indole compounds and using computer simulations to predict which ones might work best against the virus’s key proteins.

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Bibliometric analysis of traditional Chinese medicine for viral infections through immune modulation (2015–2025)

This research analyzed over 3,300 scientific papers published between 2015-2025 to understand how traditional Chinese medicine helps fight viral infections by boosting the immune system. The study found that research on this topic has grown significantly, especially during disease outbreaks like COVID-19, with China leading in research publications. Key findings show that traditional Chinese herbal compounds work through multiple mechanisms including directly fighting viruses, reducing excessive inflammation, and enhancing vaccine effectiveness. The research points toward promising future applications of traditional Chinese medicine when combined with modern medical approaches.

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Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

Researchers screened 167 extracts from 36 medicinal fungi to find natural compounds that could fight COVID-19. They discovered that certain fungi, particularly Inonotus obliquus and Pholiota adiposa, contain polysaccharides that effectively block the virus from infecting cells. These natural compounds showed promise as potential safe alternatives for developing new COVID-19 treatments and may have applications against other viral diseases.

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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

Researchers discovered that a virus infecting the dangerous fungus Aspergillus fumigatus actually helps the fungus survive and cause worse infections in humans. By removing the virus from fungal strains, scientists found that the fungus became weaker and less able to cause disease in mice. Importantly, treating infected mice with an antiviral drug (ribavirin) reduced the viral load and helped the mice survive, suggesting a new approach to treating serious fungal infections.

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Introduction to Traditional Medicine and Their Role in Prevention and Treatment of Emerging and Re-Emerging Diseases

This article explores how traditional medicine systems like Ayurveda and Chinese Medicine can help prevent and treat infectious diseases, including COVID-19. These ancient healing systems use natural herbs and lifestyle changes to boost immunity and fight infections more holistically. Scientific evidence shows that natural compounds like curcumin from turmeric have real antiviral and anti-inflammatory properties. By combining traditional knowledge with modern research, we may develop better treatments for emerging diseases.

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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

A virus that infects the fungus Aspergillus fumigatus makes the fungus more dangerous by helping it survive stress and resist immune cell attack. When researchers removed the virus from the fungus, it became weaker and less harmful to infected mice. Treating infected mice with an antiviral drug called ribavirin reduced the virus, lowering fungal burden and improving survival, suggesting that targeting fungal viruses could be a new way to treat serious fungal infections.

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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

A virus that infects the fungus Aspergillus fumigatus (which causes serious lung infections in humans) actually makes the fungus more dangerous by improving its ability to survive stress and spread disease. Scientists found that removing this virus from the fungus made infections less severe in mice. They also discovered that antiviral drugs like ribavirin could potentially be used to weaken these virus-infected fungi and improve patient survival.

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