Research Keyword: antiSMASH analysis

Screening microbial inhibitors of Pseudogymnoascus destructans in Northern China

Scientists in Northern China have found bacteria living on bat skin and in cave soil that can kill the fungus responsible for white-nose syndrome, a disease devastating bat populations worldwide. These bacteria produce various antifungal compounds including volatile organic compounds that diffuse through the air and damage the fungus’s structure. By analyzing the genetic makeup of these bacteria, researchers identified specific genes responsible for producing these antifungal compounds, offering hope for developing biological control treatments that could protect bats and reduce fungal loads in cave environments.

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Identification of an antifungal lipopeptide from Bacillus amyloliquefaciens HAU3 inhibiting the growth of Fusarium graminearum using preparative chromatography and 2D-NMR

Researchers identified a soil bacterium called Bacillus amyloliquefaciens HAU3 that naturally produces fengycin, a powerful antifungal compound. This compound can kill disease-causing fungi like Fusarium graminearum that contaminate animal feed and produce harmful toxins. The bacteria also breaks down dangerous toxins called zearalenone, making it a potential natural solution for protecting livestock feed from fungal contamination.

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