Research Keyword: antioxidant

Nettle (Urtica cannabina L.) polysaccharides as a novel dietary supplement: enhancing systemic antioxidant status via modulation of the gut–liver axis

This study found that nettle polysaccharides, especially at lower doses, act as a natural supplement that boosts the body’s antioxidant defenses. The supplement works by promoting beneficial bacteria in the gut, which produce helpful metabolites that signal to the liver to enhance protective antioxidant enzymes. These findings suggest nettle polysaccharides could be a promising natural ingredient for health-conscious food products aimed at maintaining metabolic wellness.

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Health benefits of fish and fish by-products—a nutritional and functional perspective

Fish is an excellent food that provides many important nutrients like protein, omega-3 fatty acids, and vitamins that help protect our hearts, brains, and overall health. Different fish species offer various health benefits including protecting against heart disease, diabetes, obesity, and brain disorders. However, some fish can contain harmful contaminants like mercury, so choosing safer options like salmon and cod is important for children and pregnant women.

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Biological Characteristics, Domesticated Cultivation Protocol, Antioxidant Activity, and Protective Effects against Cellular Oxidative Stress of an Underutilized Medicinal Mushroom: Fomitopsis palustris

Researchers successfully grew and studied Fomitopsis palustris, a medicinal mushroom, in laboratory conditions. They discovered that the mushroom contains beneficial compounds that protect cells from damage caused by harmful free radicals. The polysaccharides extracted from the mushroom boosted the cells’ natural defense systems and reduced oxidative stress markers, suggesting potential health benefits for treating age-related and degenerative diseases.

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Whey Proteins and Bioactive Peptides: Advances in Production, Selection and Bioactivity Profiling

Whey, a liquid byproduct from cheese-making that was once considered waste, contains valuable proteins that can be broken down into smaller bioactive peptides. These peptides have numerous health benefits including antimicrobial, anti-inflammatory, and antioxidant properties, and can be used in functional foods and medicines. Researchers are developing advanced techniques to extract and produce these peptides more efficiently, and using computer models to predict which peptides will have specific health benefits.

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Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

A mixture of three medicinal mushrooms (Phellinus linteus, Ganoderma lucidum, and Inonotus obliquus) was tested for its ability to protect nerve cells from damage. The extract successfully reduced cell death in laboratory models of neurodegeneration by reducing harmful molecules called reactive oxygen species and reducing inflammation. These results suggest the mushroom extract could potentially help prevent or slow neurological diseases like Alzheimer’s.

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Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively prevent the production of aflatoxin B1, a highly toxic and cancer-causing substance produced by certain molds that contaminate crops like corn and wheat. The mushroom extracts work by inhibiting the toxin production by up to 94%, offering a natural, environmentally-friendly alternative to chemical pesticides. The study suggests that compounds in mushrooms, including special sugars and enzymes, may help protect food supplies from this dangerous contamination, which is becoming increasingly important as climate change creates more favorable conditions for mold growth.

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The Lignicolous Fungus Hericium erinaceus (Lion’s Mane Mushroom): A Promising Natural Source of Antiradical and DPPH Inhibitory Agents

Lion’s Mane mushrooms grown on a special mixture of agricultural waste materials showed the best antioxidant properties in this study. Researchers found that combining sawdust, wheat straw, bagasse, rice bran, and corn flour created the ideal growing environment. The mushrooms produced high levels of protective compounds called phenolics and flavonoids that help fight harmful free radicals in the body. This research shows how we can turn agricultural waste into valuable medicinal mushrooms with strong health benefits.

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Cultivation and mycelium production from spore suspensions of desert truffles: prospective use as inoculum for host plants in arid zones

Desert truffles are valuable edible fungi that grow in arid regions and have health benefits. This research successfully grew two desert truffle species (Terfezia boudieri and Tirmania nivea) in laboratory conditions using standard culture media. The study found that potato dextrose agar was the best medium for rapid growth, while both media supported good mycelial development. This breakthrough could enable large-scale production of truffle inoculum for reforestation programs in Morocco’s degraded desert areas.

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Chromosome-Scale Genome and Transcriptomic Analyses Reveal Differential Regulation of Terpenoid Secondary Metabolites in Hericium coralloides

Researchers sequenced the complete genome of Hericium coralloides, an edible medicinal mushroom, at the chromosome level for the first time. They identified genes responsible for producing terpenoids, which are beneficial compounds with antioxidant, anti-inflammatory, and anti-tumor properties. The study found that these beneficial compounds are produced in higher amounts in the mushroom’s mycelium (root-like structure) compared to fruiting bodies, which could help optimize mushroom cultivation for medicinal use.

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