Research Keyword: antioxidant therapy

Polysaccharides from fungi: A review on their extraction, purification, structural features, and biological activities

Mushrooms contain special compounds called polysaccharides that have powerful health benefits. Scientists have found these polysaccharides can help fight cancer, boost immunity, reduce inflammation, and manage diabetes. This review explains different ways to extract and purify these beneficial compounds from mushrooms and describes how they work in the body to provide these health benefits.

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Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

Morel mushrooms are prized edible fungi that unfortunately degrade when repeatedly cultured in the laboratory, becoming slower-growing and less productive. Researchers used advanced genetic and chemical analysis to discover that degeneration occurs when the mushroom stops producing flavonoids, natural antioxidants that protect cells from damage. A specific gene called NR-PKS is responsible for making these protective flavonoids, and it shuts down in degraded strains. The study suggests that preservation methods using cold storage or adding antioxidants could help maintain healthy, productive morel cultures.

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Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

Mushrooms are nutritious superfoods packed with protein, fiber, vitamins, and minerals that support overall health. They contain special compounds that can fight inflammation, boost immunity, and help prevent serious diseases like cancer and diabetes. Beyond eating them, mushrooms are being used to make medicines, cosmetics, and animal feed, while also helping clean up polluted environments. Regular consumption of mushrooms offers significant health benefits and can be a valuable addition to any healthy diet.

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Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

Morel mushrooms lose quality when repeatedly cultured in laboratories, becoming slower-growing and less vibrant. Scientists discovered this happens because genes controlling antioxidant production shut down, allowing harmful free radicals to damage cells. By avoiding frequent subculturing and using cold storage or antioxidant supplements, farmers can keep their morel strains healthy and productive for longer.

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Ganoderma lucidum and Robinia pseudoacacia Flower Extract Complex Alleviates Kidney Inflammation and Fibrosis by Modulating Oxidative Stress

Researchers studied a natural supplement made from reishi mushroom and black locust flower to treat kidney disease. In laboratory and animal tests, this supplement reduced kidney damage by lowering harmful molecules called free radicals and controlling inflammation. The supplement worked by blocking specific pathways that cause kidney inflammation and scarring, suggesting it could be a helpful natural treatment for people with chronic kidney disease.

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Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

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Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Ziziphora bungeana Juz. Extracts

Ziziphora bungeana, a traditional medicinal plant from Kazakhstan, was studied for its health benefits. Scientists found it contains powerful plant compounds that fight bacteria and fungal infections, especially those causing skin problems. The extracts work similarly to commercial skin-lightening agents and show promise for treating infections and skin conditions without significant harm to healthy cells.

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Ornithine enhances common bean growth and defense against white mold disease via interfering with SsOAH and diminishing the biosynthesis of oxalic acid in Sclerotinia sclerotiorum

Researchers found that L-ornithine, a naturally occurring amino acid, can help common bean plants defend themselves against white mold disease caused by the fungus Sclerotinia sclerotiorum. When applied to bean plants, ornithine boosted their antioxidant defenses and interfered with the fungus’s ability to produce oxalic acid, a toxic compound it uses to infect plants. This discovery offers farmers a potential eco-friendly alternative to chemical fungicides for protecting bean crops.

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Eco-friendly biosynthesis of silver nanoparticles using marine-derived Fusarium equiseti: optimization, characterization, and evaluation of antimicrobial, antioxidant, and cytotoxic activities

Scientists used a marine fungus called Fusarium equiseti to create tiny silver particles called nanoparticles in an environmentally-friendly way. These particles showed strong abilities to kill harmful bacteria and fungi, protect cells from damage caused by free radicals, and fight breast cancer cells in laboratory tests. This green synthesis method offers a safer, non-toxic alternative to traditional chemical manufacturing while producing stable, multi-functional nanoparticles.

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Evaluating the antioxidant, anti-inflammatory, and neuroprotective potential of fruiting body and mycelium extracts from edible yellow morel (Morchella esculenta L. Pers.)

This study examined morel mushrooms from Pakistan to see if they could help treat Alzheimer’s disease and related brain conditions. Researchers tested both the fruiting bodies and the root-like mycelia of Morchella esculenta mushrooms for their ability to fight oxidative stress, reduce inflammation, and inhibit an enzyme that breaks down acetylcholine, a brain chemical important for memory. The results showed that morel extracts, especially from fruiting bodies collected in certain regions, worked as well as or better than conventional medications, suggesting these common edible mushrooms could be developed into treatments for neurodegenerative diseases.

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