Research Keyword: antioxidant capacity

Optimization of Ultrasonic Extraction to Obtain Erinacine A and Polyphenols with Antioxidant Activity from the Fungal Biomass of Hericium erinaceus

Researchers developed an efficient ultrasonic extraction method to obtain beneficial compounds from the lion’s mane mushroom (Hericium erinaceus), particularly a substance called erinacine A and antioxidants. The optimized process uses 80% ethanol and takes 45 minutes, producing extracts rich in antioxidants that can protect cells from damage. These extracts showed promise in protecting brain cells and could potentially help prevent or treat neurodegenerative diseases like Alzheimer’s disease.

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Integrated Transcriptomics and Metabolomics Provide Insight into Degeneration-Related Molecular Mechanisms of Morchella importuna During Repeated Subculturing

Morel mushrooms (Morchella importuna) lose quality when repeatedly grown from cultured samples, a process called strain degeneration. Scientists found that degenerated strains have lower levels of beneficial compounds called flavonoids, which normally protect mushroom cells from damage. By studying gene expression and metabolite changes, researchers identified a specific gene responsible for making these protective flavonoids, which becomes less active in degenerated strains. This research suggests that avoiding frequent reculturing and maintaining cold storage or adding antioxidants could help preserve healthy morel mushroom strains.

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Chemical Composition, Bioactive Compounds, and Antioxidant Activity of Two Wild Edible Mushrooms Armillaria mellea and Macrolepiota procera from Two Countries (Morocco and Portugal)

This study compared two edible wild mushrooms (honey fungus and parasol mushroom) from Morocco and Portugal to understand their health benefits. Both mushrooms were found to be rich in compounds with antioxidant properties that help protect cells from damage. The research shows that where mushrooms grow—whether in Morocco or Portugal—affects their chemical makeup and healing potential, with Moroccan honey fungus showing particularly strong antioxidant power.

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Persister cells in human fungal pathogens

Some fungal infections fail to respond to antifungal drugs even when the fungus should be susceptible to treatment. This happens because certain fungal cells can enter a dormant ‘sleep-like’ state that helps them survive drug exposure. These dormant cells, called persisters, are able to hide from medications by reducing their metabolism and enhancing their protective defenses. Understanding how these persister cells form and survive could lead to better treatments for serious fungal infections.

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Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broilers

Researchers studied how a medicinal mushroom extract called Phellinus linteus polysaccharides could help broiler chickens recover from immune stress caused by bacterial toxins. The supplement improved the chickens’ growth, reduced harmful inflammatory responses, and promoted beneficial gut bacteria while reducing harmful ones. The treatment strengthened the intestinal barrier and restored the chickens’ natural antioxidant defenses. This suggests the mushroom supplement could be a natural alternative to antibiotics for improving poultry health on farms.

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Multiomics Provides a New Understanding of the Effect of Temperature Change on the Fermentation Quality of Ophiocordyceps sinensis

This research studied how temperature affects the growth and quality of Ophiocordyceps sinensis, a valuable medicinal fungus. Scientists found that the fungus grows best between 18-23°C, and that temperatures above 28°C damage the fungus by triggering cell death processes. The study identified which genes and metabolites are affected by temperature changes, helping optimize large-scale production of this medicinal fungus.

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Chemical profile and bioactivity of essential oils from five Turkish thyme species against white mold fungal disease agent Sclerotinia sclerotiorum

Researchers studied five types of Turkish thyme plants to see if their essential oils could fight a harmful fungus called Sclerotinia sclerotiorum that damages crops like cucumbers and sunflowers. They found that thyme oils, especially those rich in carvacrol and thymol, were very effective at stopping fungal growth. These natural plant oils could be used as safer alternatives to chemical fungicides in farming, reducing environmental damage while controlling plant diseases.

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Optimizing and Characterization of Soybean Oil Seed Cake Protein Hydrolysis: In Vitro Analysis

Researchers successfully created a high-protein powder from soybean processing waste by breaking down proteins using special enzymes. The resulting powder contains 60% protein and shows promising health benefits including antioxidant properties and the ability to slow glucose absorption, making it potentially useful for managing diabetes and obesity. This converts a low-value agricultural byproduct into a valuable ingredient for food and pharmaceutical applications.

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Comparison of Different Extraction Solvents for Characterization of Antioxidant Potential and Polyphenolic Composition in Boletus edulis and Cantharellus cibarius Mushrooms from Romania

This research compared how well four different liquids extract beneficial compounds from two popular edible mushrooms: porcini (Boletus edulis) and chanterelle (Cantharellus cibarius). The study found that a simple acidic water solution was the best at pulling out healthy antioxidant compounds and polyphenols from these mushrooms. These antioxidants help protect cells from damage, making them potentially beneficial for health.

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Lipid Fraction from Agaricus brasiliensis as a Potential Therapeutic Agent for Lethal Sepsis in Mice

Researchers tested a special extract from the Agaricus brasiliensis mushroom (rich in a compound called ergosterol) to treat severe sepsis, a life-threatening blood infection, in mice. When mice were given this mushroom extract alone, 67% survived, and when combined with antibiotics, 100% survived compared to none with saline alone. The extract reduced inflammation, protected the liver, fought bacteria, and reduced harmful free radicals in the body, suggesting it could be a valuable addition to antibiotic treatment for sepsis.

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