antimicrobial therapy

Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles

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Periodontitis is a serious gum disease that causes tooth loss and affects overall health. This review examines how polysaccharides (complex carbohydrates) from plants and fungi can help treat periodontitis by reducing inflammation, fighting bacteria, and helping gum tissue repair. These natural compounds work through multiple biological pathways to improve oral health outcomes while avoiding the side effects and resistance problems associated with conventional drugs.

Atypical Cutaneous Manifestation of Mycosis Fungoides: A Case Report

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A 68-year-old woman with mycosis fungoides, a rare skin cancer, developed severe infected lesions after swimming in the ocean. Her wounds were infected with four different types of bacteria that had not been previously reported together in this disease. She was treated with antibiotics and improved, highlighting the importance of patients with this condition avoiding water exposure and maintaining regular medical care.

Tinea incognito skin lesions worsen after antifungal treatment: Atypical tinea appearing twice in a case: A case report

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A young woman had a persistent facial rash for 10 months that was initially misdiagnosed as dermatitis because early fungal tests were negative. When fungal testing was repeated, it finally confirmed a fungal infection (tinea incognito) caused by contact with a dog. Treatment with antifungal medication alone initially worsened the condition by causing bacterial infection, but combining antifungal and antibiotic medications resolved it. The infection returned after using the same contaminated skincare products, but was successfully treated again with the combined medication approach.

Harnessing the Nutritional Value, Therapeutic Applications, and Environmental Impact of Mushrooms

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Mushrooms are nutritious superfoods packed with protein, fiber, vitamins, and minerals that support overall health. They contain special compounds that can fight inflammation, boost immunity, and help prevent serious diseases like cancer and diabetes. Beyond eating them, mushrooms are being used to make medicines, cosmetics, and animal feed, while also helping clean up polluted environments. Regular consumption of mushrooms offers significant health benefits and can be a valuable addition to any healthy diet.

Fruiting body-associated Pseudomonas contact triggers ROS-mediated perylenequinone biosynthesis in Shiraia mycelium culture

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Scientists discovered that bacteria living inside medicinal mushroom fruiting bodies can trigger the production of powerful healing compounds called perylenequinones through direct physical contact. These compounds are being used to fight cancer and harmful bacteria through a therapy called photodynamic therapy. The study shows that when bacteria touch the mushroom’s cells, it causes the mushroom to produce more of these therapeutic compounds by creating controlled stress that activates specific genes.

Production of fungal hypocrellin photosensitizers: Exploiting bambusicolous fungi and elicitation strategies in mycelium cultures

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Hypocrellins are powerful compounds from fungi that can treat cancers and infections through light-activated therapy. Since wild sources are limited, scientists are growing these fungi in laboratory cultures and using special techniques to boost production. This review summarizes the best methods for producing hypocrellins, from choosing the right fungal strains to optimizing growing conditions and using natural stimulants to increase yields.

Bacterial and Fungal Pathogens in Chronic Suppurative Otitis Media and Otitis Externa With Persistent Otorrhea: A Cross-Sectional Study in a Low- to Middle-Income Country (Pakistan)

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This study examined ear infections in Karachi, Pakistan, identifying which bacteria and fungi cause chronic ear drainage. Researchers found that Pseudomonas bacteria and Aspergillus fungi were the most common culprits, often appearing together. The warm, humid climate and poor sanitation in the area contribute to these infections, which need better diagnostic testing and tailored treatment approaches to improve patient outcomes.

Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

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Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

Eco-friendly biosynthesis of silver nanoparticles using marine-derived Fusarium equiseti: optimization, characterization, and evaluation of antimicrobial, antioxidant, and cytotoxic activities

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Scientists used a marine fungus called Fusarium equiseti to create tiny silver particles called nanoparticles in an environmentally-friendly way. These particles showed strong abilities to kill harmful bacteria and fungi, protect cells from damage caused by free radicals, and fight breast cancer cells in laboratory tests. This green synthesis method offers a safer, non-toxic alternative to traditional chemical manufacturing while producing stable, multi-functional nanoparticles.

Necrotizing orbital infections: A comprehensive review

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Necrotizing orbital infections are serious, fast-spreading infections around the eye caused by bacteria, fungi, or viruses. These infections can cause vision loss and can be life-threatening, especially for people with weakened immune systems. Quick diagnosis and aggressive treatment with antibiotics or antifungal medications, combined with surgery to remove infected tissue, are essential to save sight and prevent death.

Research Keyword: antimicrobial therapy