Research Keyword: antimicrobial susceptibility testing

Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

This study surveyed 131 medical laboratories across 28 African countries to understand what types of infectious disease testing they can perform. Researchers found that while most labs can test for parasites and bacteria, fewer can perform tests for viruses (except HIV) or fungi. The study identified that HIV testing is widely available, but better access to other viral and fungal disease testing is needed to improve healthcare and prepare for future disease outbreaks.

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Prospective Study on Microbiological Profile of Fungal Isolates and its Antibiogram in a Tertiary care hospital in South India

Researchers studied fungal infections in a hospital in South India over one year, examining 62 fungal isolates. They found that Candida auris, a dangerous fungal species, was the most common and had developed resistance to many antifungal drugs. A newer class of antifungal drugs called echinocandins worked best against these infections, highlighting the importance of quick identification of fungal species for proper treatment.

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Severe Saprochaete capitata fungemia presenting as micafungin breakthrough hepatosplenic lesions in an immunocompromised patient: case report

A 70-year-old woman with blood cancer developed a serious fungal blood infection caused by Saprochaete capitata, a rare soil fungus, despite taking preventive antifungal medication. The infection spread to her liver and spleen, creating multiple lesions and a dangerous aneurysm. Doctors successfully treated her with a combination of three antifungal drugs, particularly voriconazole, which proved more effective than the initial preventive medication. This case highlights how rare fungi can cause severe infections in cancer patients and the importance of recognizing when standard preventive treatments are not working.

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Survey of clinical microbiology and infectious disease testing capabilities among institutions in Africa

This study surveyed laboratory facilities across Africa to understand what infectious disease tests are available. Researchers found that basic tests like bacterial identification are common, but advanced tests for viruses (other than HIV) and fungi are less available. The study highlights the need for investment in laboratory infrastructure to improve disease diagnosis and help countries respond to health emergencies.

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