Research Keyword: antimicrobial resistance

Biological applications of yttrium oxide nanocomposites synthesized from Aspergillus penicillioides and their potential role in environmental remediation

Researchers used a fungus called Aspergillus penicillioides to create tiny particles of yttrium oxide that can remove dangerous metals like lead and nickel from contaminated water. These particles work like microscopic sponges that grab onto the toxic metals when exposed to UV light. The particles also kill bacteria and fight harmful free radicals, making them useful for both cleaning water and potentially treating infections.

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The Impact of the Fungal Priority Pathogens List on Medical Mycology: A Northern European Perspective

Fungal infections affect over a billion people worldwide but are often overlooked in healthcare. The World Health Organization recently created a priority list of dangerous fungi to help doctors and researchers focus their efforts. This review discusses how this list can improve diagnosis, testing, and treatment of fungal infections across Europe, while also highlighting the need for better training and awareness among healthcare workers.

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Antifungal Potential of Streptomyces-Derived Metabolites Against Fluconazole-Resistant Oral Candida albicans: In vitro Evaluation and Mechanistic Insights

Researchers studied a type of soil bacteria called Streptomyces that produces natural compounds with strong antifungal properties. These compounds effectively killed drug-resistant Candida fungal infections that commonly affect cancer patients undergoing radiation therapy. The bacterial extract worked by damaging fungal cell membranes and blocking biofilm formation, which are protective structures the fungus uses to survive. While the results are promising for treating stubborn fungal infections, more research is needed to ensure safety for human patients.

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Spread of Antifungal-Resistant Trichophyton indotineae, United Kingdom, 2017–2024

A dangerous fungal infection called Trichophyton indotineae is rapidly spreading across the United Kingdom, particularly among people with connections to South Asia. This infection causes stubborn skin rashes that don’t respond well to common antifungal treatments like terbinafine. The number of cases has skyrocketed, making up 38% of all dermatophyte infections by 2024, and doctors need to be aware of this emerging threat.

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Genomic Insights into Vaccinium spp. Endophytes B. halotolerans and B. velezensis and Their Antimicrobial Potential

Scientists discovered that wild berries like blueberries, cranberries, and lingonberries contain beneficial bacteria that can fight harmful fungi and bacteria. These bacteria produce natural antimicrobial compounds similar to how antibiotics work, making them promising candidates for protecting crops without chemical pesticides. The bacteria also help plants absorb nutrients and cope with stress, offering multiple benefits for sustainable agriculture.

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Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

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Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Ziziphora bungeana Juz. Extracts

Ziziphora bungeana, a traditional medicinal plant from Kazakhstan, was studied for its health benefits. Scientists found it contains powerful plant compounds that fight bacteria and fungal infections, especially those causing skin problems. The extracts work similarly to commercial skin-lightening agents and show promise for treating infections and skin conditions without significant harm to healthy cells.

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Antifungal Policy and Practice Across Five Countries: A Qualitative Review

This study examines how well five different countries handle invasive fungal infections through their healthcare policies and systems. Researchers found that while these infections affect millions of people globally, most countries lack comprehensive policies to diagnose, treat, and manage them effectively. Major issues include inadequate healthcare provider training, limited access to rapid diagnostic tests, and insufficient antifungal medications in some regions. The study recommends that countries develop better national strategies for preventing, diagnosing, and treating these serious infections.

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Emergence of resistant dermatophytosis caused by Trichophyton indotineae: First case series in Thailand

Doctors in Thailand have identified a new drug-resistant fungal infection caused by Trichophyton indotineae, a fungus that doesn’t respond to common antifungal medication terbinafine. Five patients were diagnosed with this resistant skin infection that caused rashes on various body parts and failed to improve with standard treatments. The research shows that a simple urease test can help doctors quickly identify this resistant fungus, and a different drug called itraconazole appears to work better for treatment. This is the first time this resistant fungus has been confirmed in Thailand, suggesting it is spreading globally.

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