antifungal – Page 3

Bacterial–Fungal Interactions: Mutualism, Antagonism, and Competition

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Bacteria and fungi in animal bodies interact in three main ways: they help each other (mutualism), fight each other (antagonism), or compete for resources. These interactions happen in the gut, rumen, and skin of animals. Understanding how to balance these relationships can help create better probiotics and natural alternatives to antibiotics for treating infections and improving animal health.

Transcriptome Analysis of Dimethyl Fumarate Inhibiting the Growth of Aspergillus carbonarius

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Researchers studied how a chemical called dimethyl fumarate stops the growth of a dangerous fungus (Aspergillus carbonarius) that damages grapes and produces a toxin called ochratoxin A. By analyzing which genes were turned on and off when the fungus was exposed to this chemical, they found that it works by damaging the fungus’s cell walls and disrupting its normal development. This discovery could help protect fruit crops and food safety by providing a natural and non-toxic way to prevent mold growth.

One-Health Approach to Managing Aflatoxin-Producing Aspergillus flavus Using Spent Mushroom Substrate of Pleurotus spp

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This study shows that leftover substrate from growing oyster and red mushrooms can work together with a common antifungal fungicide to better prevent harmful Aspergillus fungi from contaminating corn. The combination of mushroom waste and fungicide was more effective than using either alone, and could potentially reduce the amount of chemicals needed in agriculture while protecting the environment and preventing drug resistance.

Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

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This research demonstrates that clove oil, a natural and FDA-approved dietary supplement, can effectively combat Candida albicans infections that cause vaginal yeast infections. The study found that clove oil works by preventing the fungus from forming protective biofilms and by reducing inflammation. In mice with vaginal yeast infections, clove oil treatment significantly improved symptoms and reduced fungal levels, suggesting it could serve as a safer alternative to conventional antifungal medications.

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

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Researchers found that an extract from Cinchona bark, containing the compound quinine, effectively kills rice-damaging fungus Rhizoctonia solani through two mechanisms: starving the fungus of the amino acid tryptophan and disrupting its energy-producing mitochondria. This natural plant-based treatment could serve as an eco-friendly alternative to synthetic fungicides, reducing crop losses from fungal diseases while avoiding the environmental damage and resistance problems associated with chemical pesticides.

The Efficacy of Clove Oil Against Aspergillus flavus and the Production of Aflatoxin B1 in Organic Peanuts in Georgia

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Researchers tested clove essential oil as a natural antifungal treatment for peanuts infected with a mold that produces aflatoxin, a dangerous toxin harmful to human health. They found that clove oil significantly reduced both the mold growth and toxin production, with the best results at moderate concentrations. This discovery offers organic farmers an eco-friendly alternative to synthetic fungicides for protecting their peanut crops. The findings could help reduce a major agricultural problem that costs the Southeast millions of dollars annually.

Sandalwood Sesquiterpene (Z)-α-Santalol Exhibits In Vivo Efficacy Against Madurella mycetomatis in Galleria mellonella Larvae

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Researchers tested sandalwood compounds against a fungal infection that causes a tropical disease called eumycetoma. Using a laboratory model with wax moth larvae infected with the fungus, they found that a specific compound called (Z)-α-santalol significantly extended the survival of infected larvae. This compound was more effective than current antifungal drugs and showed promise as a potential new treatment for this neglected tropical disease.

Complete genome analysis and antimicrobial mechanism of Bacillus velezensis GX0002980 reveals its biocontrol potential against mango anthracnose disease

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Researchers found a beneficial bacterium called Bacillus velezensis that can effectively fight the fungus causing brown spots on mangoes. The bacterium produces natural antibiotic compounds that kill the disease-causing fungus and can be sprayed on mangoes to keep them fresh longer during storage. This discovery offers a safer, eco-friendly alternative to harsh chemical fungicides for protecting the mango harvest.

Chemical profile and bioactivity of essential oils from five Turkish thyme species against white mold fungal disease agent Sclerotinia sclerotiorum

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Researchers tested essential oils from five different thyme species grown in Turkey against a common plant fungus that causes white mold disease. They found that oils rich in carvacrol, particularly from Thymbra spicata and Satureja cilicica, were very effective at stopping fungal growth. These natural oils could be used as environmentally friendly alternatives to chemical pesticides in farming.

Study on the inhibitory mechanism of fig leaf extract against postharvest Fusarium in melon

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Researchers discovered that fig leaves contain natural compounds that can prevent fruit rot caused by Fusarium fungus in melons. When applied to infected melons, the fig leaf extract kills the fungus by damaging its cell membranes and overwhelming it with harmful molecules called reactive oxygen species. This natural treatment could replace chemical fungicides that harm the environment and leave residues on food, offering a safer way to preserve melons during transport and storage.

Research Keyword: antifungal