Research Keyword: antifungal treatment

Fusarium Corneal Abscess: A Case Report

A healthy 20-year-old man developed a serious fungal eye infection caused by Fusarium, a soil fungus, despite having no typical risk factors like eye injury or contact lens wear. Doctors diagnosed the infection through laboratory tests showing fungal filaments and growing the organism in culture. The patient required multiple treatments including antifungal eye drops, injections directly into the cornea, and a graft from amniotic membrane (placenta tissue) to save his vision. The case demonstrates that fungal eye infections can occasionally occur in completely healthy people without obvious causes.

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First Report of Trametes hirsuta, Causal Agent White Rot in Avocado Trees Grown in the State of Michoacán, México

Researchers discovered a wood-destroying fungus called Trametes hirsuta causing serious disease in avocado trees in Mexico’s main avocado-growing region. The fungus attacks tree trunks and branches, causing white rot that can kill trees within 3-5 years. The study confirmed this is a new threat to avocado orchards and suggests controlling it through pruning, chemical fungicides, or biological control methods.

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ABPA in post-tuberculosis lung disease: A diagnostic pitfall or genuine entity?

After tuberculosis treatment, some patients develop fungal lung infections that can look very similar to an allergic fungal disease called ABPA. This editorial warns doctors that they need to be careful about diagnosing ABPA in tuberculosis patients because treating it with the wrong medications could make the fungal infection worse. The key difference is that true ABPA causes wheezing and asthma-like symptoms, while post-TB fungal infections cause cavities and scarring in the lungs.

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A Review on Aspergillosis in Turkey: As a Main Fungal Disease in Poultry

Aspergillosis is a serious fungal disease affecting turkeys, especially young birds, caused by breathing in fungal spores from moldy hay, compost or poorly ventilated housing. The disease causes respiratory problems, can spread to other organs, and can kill 30-50% of affected flocks. Prevention through good ventilation, clean housing and dry feed is more effective than treatment since few antifungal drugs are approved for food animals. Understanding how environmental conditions promote this disease is key to protecting turkey populations.

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Northwest Iranian dermatophyte isolates: anthropophilic and geophilic

Researchers in northwestern Iran studied fungal infections of skin, hair, and nails by identifying different types of dermatophytes from patient samples and soil. They found that a fungus called Trichophyton mentagrophytes was the most common cause, but also discovered a rare fungus called Myriodontium keratinophilum causing nail infections. Using modern DNA testing methods, they identified seven different dermatophyte species and several other soil fungi, providing important information about fungal infections in this region.

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Cracks in the Curriculum: The Hidden Deficiencies in Fungal Disease Coverage in Medical Books

Medical textbooks used to train doctors contain significant gaps in their coverage of fungal infections, which cause millions of deaths annually. While infectious disease textbooks provide better information than general internal medicine textbooks, all of them fall short in covering important topics like diagnosis methods and prevention strategies. The study found that doctors and students relying solely on these textbooks may not have adequate knowledge to properly diagnose and treat fungal infections, which could impact patient care outcomes.

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Superficial Fungal Infections in the Pediatric Dermatological Population of Northern Poland

This study examined fungal skin infections in children and teens in Northern Poland over six years, finding that about 1 in 5 children tested had a fungal infection. Different types of fungal infections were more common at different ages—younger children more often had scalp infections, while teenagers more often had foot and nail infections. The study found that children living in rural areas had higher infection rates than those in cities, suggesting that environmental factors play an important role in fungal infection patterns.

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Antimicrobial effects and mechanisms of hydrogen sulphide against nail pathogens

Researchers discovered that hydrogen sulphide (H2S), a small gas molecule, can effectively kill the fungi and bacteria that cause painful nail infections. Unlike current treatments that struggle to penetrate into the nail, hydrogen sulphide easily diffuses through the nail plate. The study found that H2S works by damaging the fungi’s respiratory system and creating harmful reactive oxygen species, while also modifying proteins in a way that disrupts their normal function. This innovative approach could offer patients a new topical treatment option for nail infections that have been difficult to treat with existing medications.

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Epidemiological Profile of Otomycosis at the Peace Hospital of Ziguinchor (Senegal)

This study examined fungal ear infections in a hospital in Senegal and found that about 85% of suspected cases were actually caused by fungi. The most common fungi were Aspergillus and Candida species. The research shows that itching was the main symptom associated with fungal ear infections, and that proper diagnosis is important to avoid unnecessary antibiotic use and provide better treatment.

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Coexistence of Malassezia Species and Microsporum canis in the Lesions of Adult with Tinea Capitis

A 60-year-old woman developed unusual hair loss and scalp inflammation that looked like dandruff but was actually a fungal infection caused by multiple fungi working together. Doctors found three different fungi in her scalp samples: one dermatophyte and two Malassezia species. Lab experiments showed that the Malassezia fungi actually helped the main disease-causing fungus grow better, which explains why the condition looked different from typical cases. After three months of antifungal medication, her symptoms cleared and her hair grew back.

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