antifungal susceptibility – Page 4

Onychomycosis in the US Pediatric Population—An Emphasis on Fusarium Onychomycosis

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This study examined nail fungus infections in American children using advanced molecular testing. Researchers found that elementary school-aged children (ages 6-11) have the highest rates of nail fungus, usually caused by common fungi like Trichophyton rubrum. Notably, Fusarium, an environmental fungus that was once rare in nail infections, is becoming increasingly common, especially in older teenagers, which may require different treatment approaches.

Candida tropicalis Fungal Keratitis: A Case Report and Literature Review

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A 66-year-old patient with a long history of corneal problems developed a serious eye infection caused by a fungus called Candida tropicalis. Doctors identified the infection through laboratory tests and treated it successfully with antifungal medications. This is the first documented case of this particular fungal infection in Morocco and highlights the importance of testing for fungal infections in patients with existing eye problems.

Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

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Researchers studied fungi living in sand and water along Persian Gulf beaches to understand potential health risks for swimmers. They found that fungal species, particularly Aspergillus terreus, were abundant in beach sand, with some fungi showing resistance to common antifungal medicines. The study suggests beaches need better monitoring and sanitation practices to protect public health, especially during busy bathing seasons when many visitors enjoy the coast.

Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

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Mucormycosis is a dangerous fungal infection that kills many immunocompromised patients. Researchers analyzed the outer layer (cell wall) of three common disease-causing fungi and discovered that their surfaces contain sugar-like molecules that trigger strong inflammatory responses from the immune system. This excessive inflammation may actually contribute to the disease’s severity, suggesting that controlling inflammation alongside antifungal treatment might improve patient outcomes.

Deep cutaneous fungal infection in an immunocompetent individual caused by a biological pesticide: a rare case report

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A 66-year-old farmer developed a deep skin fungal infection from a biological pesticide she used for over 10 years. The pesticide contained a fungus called Purpureocillium lilacinum, which is normally harmless to healthy people but caused repeated skin lesions on her face and arms. She was successfully treated with antifungal medication (itraconazole) for three months, and her skin fully healed without returning. This is the first reported case showing that biological pesticides can pose health risks to workers who handle them regularly.

Timely diagnosis and management of Quambalaria cyanescens-induced peritoneal dialysis peritonitis: A rare case highlighting the role of galactomannan testing

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A 53-year-old man on peritoneal dialysis developed a rare fungal infection caused by Quambalaria cyanescens. Doctors used a special blood test (galactomannan testing) to quickly identify it as a fungal infection rather than a bacterial one, leading to timely removal of his dialysis catheter on day 5. After treatment with antifungal medications, he recovered completely with no relapses over two years of follow-up. This case shows the importance of proper hygiene during dialysis and using advanced diagnostic tools for rare infections.

Feline Cryptococcosis due to Cryptococcus gattii VGII (Recently Renamed as C. deuterogattii) in an FIV-Positive Cat With Demodicosis From Manaus, Central Amazon, Brazil

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A 20-month-old cat from Brazil’s Amazon region presented with nasal discharge, skin lesions, and a neck mass and was diagnosed with cryptococcosis caused by a dangerous fungus called C. deuterogattii. The cat was also infected with feline immunodeficiency virus (FIV), which weakened its immune system and made it vulnerable to the fungal infection. Treatment with the antifungal medication fluconazole successfully cured the infection within 8 weeks, and the cat made a full recovery.

Targeted long-read sequencing analysis and antifungal susceptibility profiles of Sporothrix schenckii isolates from Thailand

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Researchers in Thailand studied a fungal infection called sporotrichosis by using advanced DNA sequencing technology to identify the exact species and understand how different strains are related to each other. They found that while current treatment options work, some strains are becoming resistant to the main drug used (itraconazole). The study shows that a newer, faster DNA sequencing method can be just as reliable as traditional methods for identifying these dangerous fungi and tracking how they spread between cats and humans.

Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient

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A peritoneal dialysis patient contracted a rare fungal infection caused by Arthrocladium tropicale, a mold found in damp environments and associated with ant nests. The infection was diagnosed through microscopy and genetic testing, revealing resistance to one antifungal drug but susceptibility to amphotericin B. Treatment with this antibiotic and removal of the dialysis catheter led to full recovery, highlighting the importance of keeping medical equipment storage areas dry and pest-free.

Insights into Persian Gulf Beach Sand Mycobiomes: Promises and Challenges in Fungal Diversity

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Researchers studied fungi in beach sand and water along the Persian Gulf and Sea of Oman coasts during summer months. They found high levels of potentially harmful fungi, especially Aspergillus terreus, which can cause serious respiratory infections. Many of these fungi showed resistance to common antifungal medications. The study recommends better hygiene awareness for beach visitors and establishing safety standards for these popular recreational areas.

Research Keyword: antifungal susceptibility