antifungal efficacy – mycolab.ai

Chitosan-mediated copper nanohybrid attenuates the virulence of a necrotrophic fungal pathogen Macrophomina phaseolina

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Researchers developed tiny copper particles coated with chitosan (a natural compound from shellfish) that effectively kill a destructive fungus called Macrophomina phaseolina, which damages hundreds of plant species worldwide. When used at the right concentration, these nanoparticles completely stopped the fungus from growing while causing minimal damage to plants. This innovation offers a promising natural alternative to traditional chemical fungicides for protecting crops while being more environmentally friendly and sustainable.

Isolation and Identification of Postharvest Rot Pathogens in Citrus × tangelo and Their Potential Inhibition with Acidic Electrolyzed Water

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Tangelo fruits suffer from fungal rot during storage caused primarily by two fungi: Penicillium citrinum and Aspergillus sydowii. Researchers tested acidic electrolyzed water (AEW), a safe and environmentally friendly treatment, and found it effectively kills these fungi by damaging their cell membranes and causing them to leak their contents. This treatment could replace harmful chemical fungicides while keeping tangelo fruits fresh and safe for consumers.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays

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Bananas are threatened by a fungal disease called Fusarium wilt that damages crops worldwide. Scientists tested tiny silver particles called nanoparticles as a treatment for this disease on banana plants. The treatment successfully reduced disease by about 68% when applied to the roots, showing promise as an alternative to traditional fungicides for protecting banana crops.

Postharvest Disease Management of ‘Akizuki’ Pear in China: Identification of Fungal Pathogens and Control Efficacy of Chlorine Dioxide

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‘Akizuki’ pears are a popular fruit in China but often develop rot diseases during storage, causing significant economic losses. Researchers identified four types of fungi responsible for this rot and tested chlorine dioxide gas as a treatment. The study found that chlorine dioxide effectively kills these fungi by damaging their cell membranes and works as well as commercial fungicides, offering a safer alternative for preserving pears without harmful chemical residues.

In vitro activity of seven antifungal agents against Fusarium oxysporum and expression of related regulatory genes

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Researchers tested seven different antifungal medications to find the best treatment for a fungal disease that damages corn crops. Epoxiconazole worked best as a single treatment, but combining pyraclostrobin and difenoconazole together was even more effective. These medications work by interfering with the fungus’s ability to survive and infect corn, making them promising options for protecting corn crops.

Isavuconazonium Utilization in Pediatric Patients at a Free-Standing Children’s Hospital

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Researchers at Children’s Hospital Los Angeles studied how well a newer antifungal medication called isavuconazonium works in children with cancer and blood disorders who are at high risk for serious fungal infections. The medication was recently approved for use in children ages 1 and older. The study found that the medication was generally safe and effective, though doctors need to monitor liver function and drug levels to ensure proper dosing and catch any side effects early.

Nano Emulsion of Essential Oils Loaded in Chitosan Coating for Controlling Anthracnose in Tomatoes (Solanum lycopersicum) During Storage

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Researchers developed a natural coating made from chitosan (a biopolymer) and thyme essential oil nano particles to protect tomatoes from a fungal disease called anthracnose during storage. When applied to tomatoes, this coating reduced disease occurrence by 50%, outperforming the commercial fungicide currently used. This eco-friendly solution offers a sustainable alternative to synthetic chemical treatments while maintaining tomato quality for longer periods.

Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

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Bananas often develop fungal infections during storage that reduce their quality. Researchers tested whether essential oils from common herbs and spices like cinnamon, clove, and oregano could prevent these fungal infections. The study found that cinnamon, clove, and oregano oils effectively stopped fungal growth at higher concentrations, offering a natural alternative to chemical fungicides that could help keep bananas fresh longer without synthetic chemicals.

Breaking the mould: challenging the status quo of clinical trial response definitions for invasive fungal diseases—a debate

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Doctors and researchers use standard definitions to determine if antifungal treatments work in clinical trials. This debate examines whether the standards created in 2008 are still appropriate today. Key concerns include whether stable disease should always count as treatment failure, how to handle deaths from other causes, and whether newer testing methods should be incorporated. The expert panel concluded these definitions need updating to reflect modern treatment options and patient needs.

Antifungal potential of copper oxide nanoparticles against Microsporum canis isolates in canine and feline dermatophytosis

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Researchers tested tiny copper oxide particles created using plant extracts against a fungus that causes ringworm in dogs and cats. These nanoparticles successfully killed the fungus in laboratory tests, with effectiveness at concentrations ranging from 500-2,000 parts per million. While slightly less effective than current medications, the nanoparticles showed promise as an alternative treatment, especially important as the fungus becomes resistant to traditional drugs.

Research Keyword: antifungal efficacy