antifungal agents – mycolab.ai

The Biological Product Agricultural Jiaosu Enhances Tomato Resistance to Botrytis cinerea

mycolabadmin

Agricultural Jiaosu is a fermented product made from plant waste that effectively controls gray mold disease in tomatoes through two mechanisms: it directly kills the fungus with organic acids, and it strengthens the plant’s natural defenses. When applied as a spray to tomato leaves once a week, it reduced disease by 55%, made plants grow taller and stronger, and boosted the plants’ protective enzymes. This natural alternative to chemical fungicides offers a sustainable and safe way to protect tomato crops while maintaining environmental health.

The Global Secondary Metabolite Regulator AcLaeA Modulates Aspergillus carbonarius Virulence, Ochratoxin Biosynthesis, and the Mode of Action of Biopesticides and Essential Oils

mycolabadmin

Grapes can be infected with a fungus called Aspergillus carbonarius that produces a dangerous toxin called ochratoxin A. Scientists studied a regulatory gene called AcLaeA that controls toxin production in this fungus. By deleting this gene, the fungus became less virulent and produced much less toxin. Natural products like cinnamon and thyme oils, along with commercial biocontrol products, were found to reduce toxin production by suppressing this regulatory gene, offering promising natural alternatives to chemical fungicides.

Feasibility of the use of Lentinula edodes mycelium in terbinafine remediation

mycolabadmin

Scientists tested whether shiitake mushrooms (Lentinula edodes) could remove terbinafine, a common antifungal medication, from contaminated environments. The mushroom mycelium successfully accumulated and broke down the drug into harmless byproducts, with no trace remaining in the surrounding medium. This eco-friendly approach offers a promising alternative to expensive chemical cleanup methods for pharmaceutical pollution.

Essential Oils as an Antifungal Alternative for the Control of Various Species of Fungi Isolated from Musa paradisiaca: Part I

mycolabadmin

Researchers tested six common cooking and medicinal herbs in oil form to see if they could kill fungi that damage bananas after harvest. Cinnamon oil was the most effective, successfully stopping all five types of harmful fungi at relatively low concentrations. The findings suggest these natural oils could replace harsh chemical fungicides used to preserve bananas during storage and transport, making banana production more environmentally friendly.

Isolation and Identification of Postharvest Rot Pathogens in Citrus × tangelo and Their Potential Inhibition with Acidic Electrolyzed Water

mycolabadmin

Tangelo fruits suffer from fungal rot during storage caused primarily by two fungi: Penicillium citrinum and Aspergillus sydowii. Researchers tested acidic electrolyzed water (AEW), a safe and environmentally friendly treatment, and found it effectively kills these fungi by damaging their cell membranes and causing them to leak their contents. This treatment could replace harmful chemical fungicides while keeping tangelo fruits fresh and safe for consumers.

Transforming Tomato Industry By-Products into Antifungal Peptides Through Enzymatic Hydrolysis

mycolabadmin

Researchers have found a way to turn tomato processing waste into useful antifungal compounds. By breaking down tomato seed proteins using enzymes, they created peptides that can prevent harmful fungi like Fusarium from growing on crops. This discovery helps reduce food waste while providing a natural alternative to chemical pesticides for protecting tomato and grain crops.

In Vitro Screening of the Antifungal and Antimycotoxin Effects of a Stilbenoids-Rich Grapevine Cane Extract on Fusarium graminearum, Aspergillus flavus and Penicillium expansum

mycolabadmin

Researchers tested an extract made from grapevine pruning waste to see if it could stop harmful fungi and the toxins they produce. The extract, rich in natural compounds called stilbenoids, successfully reduced growth and toxin production in three dangerous fungi that contaminate crops. The effects were strong enough that scientists believe this agricultural waste could become a natural alternative to chemical fungicides for protecting crops.

Antifungal and other bioactive properties of the volatilome of Streptomyces scabiei

mycolabadmin

Researchers discovered that Streptomyces scabiei, a bacterium known for causing common scab disease on potatoes and other root vegetables, produces various airborne chemicals with surprising benefits. Using advanced laboratory techniques, scientists identified 36 different volatile compounds from this bacterium, many of which can kill harmful fungi and potentially help plants grow better. While traditionally viewed as purely harmful, these findings suggest the bacterium may actually serve a more complex role in soil, sometimes protecting crops from more dangerous diseases.

Improving the production of micafungin precursor FR901379 in Coleophoma empetri using heavy-ion irradiation and its mechanism analysis

mycolabadmin

Researchers used heavy-ion radiation to create improved strains of a fungus that produces a precursor to micafungin, an important antifungal drug. The improved strains produced over 3.5 times more of the desired compound than the original strain. By analyzing the genetic changes in these improved strains, the scientists identified which genes were most important for boosting production, helping guide future improvements in manufacturing this life-saving medicine.

Sunlight-sensitive carbon dots for plant immunity priming and pathogen defence

mycolabadmin

Scientists developed special tiny carbon particles that respond to sunlight by producing molecules that strengthen plant defenses against fungi. When sprayed on plants like tomato and tobacco, these particles trigger the plant’s natural immune system, reducing fungal diseases by 12-44% without harming the plant. At higher concentrations with continuous sunlight, the particles can directly kill fungal pathogens. This eco-friendly approach offers a sustainable alternative to chemical fungicides while maintaining crop yields.

Research Keyword: antifungal agents