Research Keyword: Antifungal activity

Impact of Various Essential Oils on the Development of Pathogens of the Fusarium Genus and on Health and Germination Parameters of Winter Wheat and Maize

Researchers tested four plant-based essential oils as natural alternatives to chemical fungicides for protecting wheat and maize seeds from harmful Fusarium fungi. Thyme oil proved most effective at preventing fungal infections and seedling disease, performing as well as synthetic fungicides. However, thyme oil at higher doses harmed seed germination and plant growth, suggesting careful dose selection is needed for practical use. The findings indicate essential oils could replace chemical pesticides while maintaining crop safety, though different oils must be tested for various crops.

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Pleurotus eryngii Culture Filtrate and Aqueous Extracts Alleviate Aflatoxin B1 Synthesis

This research demonstrates that extracts from oyster mushrooms (Pleurotus eryngii) can effectively reduce dangerous aflatoxin contamination in food and feed by up to 94%. Aflatoxins are toxic compounds produced by mold fungi that can cause serious health problems including cancer. The study shows that mushroom compounds work through multiple mechanisms including antioxidant activity and enzyme production, offering a natural and environmentally friendly alternative to harmful synthetic chemicals for protecting our food supply.

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The green shield: Trichoderma’s role in sustainable agriculture against soil-borne fungal threats

This research demonstrates that Trichoderma fungi, naturally found in soil, can effectively control harmful plant-killing fungi without toxic chemicals. Scientists isolated these beneficial fungi from Kashmir soil samples and tested them against 12 destructive fungal pathogens, finding they successfully inhibited pathogen growth. The study shows promise for farmers to use these natural biocontrol agents as an environmentally friendly alternative to chemical pesticides.

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One-Pot Synthesis of Chiral Succinate Dehydrogenase Inhibitors and Antifungal Activity Studies

Scientists developed a new method to create potent antifungal medications that can protect crops from destructive fungal diseases. By carefully controlling the molecular structure (chirality) of the compounds, they created drugs that are significantly more effective and potentially less toxic than existing treatments. Testing showed that the new compound called (S)-5f works 76 times better against gray mold fungus than its mirror-image counterpart, similar to how your left and right hands have the same shape but can’t be superimposed.

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Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh

Researchers discovered several types of fungi living inside seaweed from Bangladesh’s Bay of Bengal coast. These fungi produce natural compounds that can fight bacteria, reduce harmful oxidative damage, and potentially kill cancer cells. The study identified specific chemical compounds responsible for these beneficial properties, suggesting these fungi could be useful sources for developing new medicines.

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