antifungal – mycolab.ai

Key sugar transporters drive development and pathogenicity in Aspergillus flavus

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Researchers studied how Aspergillus flavus fungus transports sugars, which is crucial for its growth, producing the toxic aflatoxin that contaminates crops like corn and peanuts. By removing genes responsible for sugar transport, they found that the fungus became weak, couldn’t infect plants or animals effectively, and stopped producing the dangerous aflatoxin. This discovery could help develop new strategies to prevent aflatoxin contamination in food and reduce serious fungal infections in humans.

Preparation and Characterization of a Novel Artemisia Oil Packaging Film and Its Application in Mango Preservation

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Researchers developed a new type of edible film made from soybean protein and gelatin infused with Artemisia oil to preserve mangoes longer after harvest. This natural, biodegradable packaging film helps prevent mango spoilage by blocking light, reducing water loss, and stopping fungal growth that causes rot. When used to wrap mangoes, the film significantly extended shelf life and maintained freshness better than unwrapped fruit, offering an environmentally friendly alternative to conventional plastic packaging.

Green Synthesis of Copper Nanoparticles from the Aqueous Extract of Lonicera japonica Thunb and Evaluation of Its Catalytic Property and Cytotoxicity and Antimicrobial Activity

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Scientists created tiny copper particles using honeysuckle plant extract in an environmentally friendly way. These particles work well for cleaning dyes from water and killing harmful bacteria and fungi. However, they can be toxic to human cells at high concentrations, so careful dosing is important for medical applications.

Valorization of Quercus suber L. Bark as a Source of Phytochemicals with Antimicrobial Activity against Apple Tree Diseases

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This research shows that waste cork from bottle stopper production contains natural compounds with strong antimicrobial properties. When combined with chitosan oligomers, these cork extracts effectively inhibit fungal and bacterial pathogens that damage apple trees. The natural antimicrobial activity was even more potent than some commercial synthetic fungicides, suggesting cork waste could provide an environmentally sustainable alternative for protecting fruit crops.

Benzothiazole—An Antifungal Compound Derived from Medicinal Mushroom Ganoderma lucidum against Mango Anthracnose Pathogen Colletotrichum gloeosporioides

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Scientists discovered that a chemical called benzothiazole found in the medicinal mushroom Ganoderma lucidum can effectively kill the fungus that causes mango anthracnose, a major disease affecting mango crops. The research showed that this natural compound completely stops fungal growth at very low concentrations (50 ppm) and prevents spore germination. This discovery offers a promising eco-friendly alternative to synthetic fungicides that can cause environmental pollution and drug resistance.

Antifungal Effect of Oregano Essential Oil Against Penicillium expansum on Pyrus sinkiangensis

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Oregano essential oil can effectively prevent blue mold rot in pears without compromising fruit quality. The oil works by damaging the fungal cell membrane, causing it to leak and die. Additionally, the treatment helps pears stay fresher longer by reducing water loss and maintaining firmness, while naturally boosting the fruit’s own defense systems against damage.

Baicalein as a potent antifungal agent against Candida albicans: synergy with fluconazole and sustainable production through probiotic-mediated bioconversion

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Baicalein, a natural compound from a traditional medicinal plant, is significantly more effective at fighting Candida albicans infections than its parent compound baicalin. When combined with the common antifungal drug fluconazole, baicalein creates a powerful synergistic effect that is especially useful against drug-resistant fungal strains. Scientists discovered that a beneficial probiotic bacterium, Lactobacillus rhamnosus, can efficiently convert the abundant baicalin into baicalein, providing a sustainable and safe way to produce this potent antifungal compound at scale.

Quillaja lancifolia Immunoadjuvant Saponins Show Toxicity to Herbivores and Pathogenic Fungi

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Researchers discovered that saponins from a Brazilian soap tree effectively kill harmful fungi and repel insects and snails, offering a natural alternative to chemical pesticides. These plant compounds work by disrupting the cell membranes of fungi and deterring herbivores from feeding. The findings suggest saponins could be used as environmentally friendly pest management tools in agriculture.

Optimization and antifungal efficacy against brown rot fungi of combined Salvia rosmarinus and Cedrus atlantica essential oils encapsulated in Gum Arabic

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Researchers have developed a natural product that protects wood from fungal decay by combining oils from rosemary and cedar trees and encapsulating them in Gum Arabic using specialized techniques. This nanoencapsulation process creates tiny protective particles that are much more stable and effective than the oils alone. When tested against wood-damaging fungi, this product showed remarkable antifungal power comparable to commercial fungicides. This innovation offers a safe, environmentally-friendly alternative to synthetic wood preservatives for building and construction applications.

Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

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Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

Research Keyword: antifungal