antibiotic resistance – Page 3

Biosynthesis of bimetallic silver–copper oxide nanoparticles using endophytic Clonostachys rosea ZMS36 and their biomedical applications

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Scientists discovered a special fungus living inside a medicinal plant that can create tiny silver-copper nanoparticles with powerful antibacterial and anti-cancer properties. These nanoparticles successfully fought dangerous bacteria like MRSA and slowed the growth of cancer cells while being safe to healthy cells. This green manufacturing method is much more environmentally friendly than traditional chemical approaches and could lead to new treatments for infections and cancer.

Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

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Researchers discovered a fungus living inside an Iranian medicinal plant that produces three natural compounds with powerful antimicrobial properties. The most promising compound, phomalactone, killed dangerous bacteria including MRSA and also prevented growth of fungal plant diseases. This discovery shows that exploring symbiotic fungi in medicinal plants could lead to new natural antibiotics and agricultural fungicides.

Microbe Profile: Streptomyces formicae KY5: an ANT-ibiotic factory

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Scientists have discovered a special bacterium called Streptomyces formicae that lives in ant nests and produces powerful antibiotics. This bacterium makes formicamycins, which can kill dangerous bacteria like methicillin-resistant Staphylococcus aureus that resists many common antibiotics. Using advanced genetic tools, researchers can modify this bacterium to unlock hidden antibiotic-producing pathways, potentially leading to new medicines to fight drug-resistant infections.

The endophytic fungus Cosmosporella sp. VM-42 from Vinca minor is a source of bioactive compounds with potent activity against drug-resistant bacteria

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Scientists discovered a fungus living inside a medicinal plant called Vinca minor that produces compounds capable of killing drug-resistant bacteria like MRSA. They isolated the main active compound, nectriapyrone, and found it effectively stops the growth of these dangerous bacteria in laboratory tests. The fungus appears to be a promising source of new antibacterial drugs that could help combat the growing problem of antibiotic-resistant infections.

Progress of Antimicrobial Mechanisms of Stilbenoids

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Stilbenoids are natural compounds found in plants that can fight harmful bacteria and fungi in multiple ways. Unlike traditional antibiotics that only kill microbes, stilbenoids can also prevent infections by disrupting biofilm formation and weakening pathogen virulence. These compounds show promise in combating drug-resistant infections without promoting further resistance development, making them valuable candidates for new antibiotic medicines.

Bioactive Properties of Selected European Phellinus Species: A Comprehensive Study

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This research examined 30 samples of medicinal mushrooms from the Phellinus genus collected across Europe, including Poland, Italy, Portugal, Kosovo, and North Macedonia. Scientists found that three species—Phellinus igniarius, Fomitiporia robusta, and Porodaedalea pini—are particularly rich in beneficial compounds, especially polysaccharides and antioxidants. These mushroom extracts showed impressive abilities to fight antibiotic-resistant bacteria and protect cells from oxidative damage, suggesting they could become valuable sources for new medicines and functional foods.

Microbe Profile: Streptomyces formicae KY5: an ANT-ibiotic factory

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Scientists discovered a special bacterium called Streptomyces formicae living with plant-ants in Africa that produces powerful antibiotics. This bacterium can kill dangerous drug-resistant bacteria and fungi that are hard to treat with current medicines. By using genetic tools, researchers are unlocking the bacterium’s hidden potential to create many more new antibiotics that could help fight infections.

First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds

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Researchers studied a Korean edible mushroom called Amanita hemibapha subsp. javanica and found it contains compounds that can kill the bacteria Helicobacter pylori, which causes stomach ulcers and gastric cancer. One compound in particular showed strong antibacterial activity, performing even better than some known antibiotics. These findings suggest this mushroom could be a natural source for developing new medicines to treat H. pylori infections and fight antibiotic-resistant strains.

Marine Fungal Metabolites: A Promising Source for Antibiofilm Compounds

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Bacteria can form protective layers called biofilms that resist antibiotics, causing serious infections. Scientists are discovering that fungi living in seaweed and marine environments produce natural compounds that can break down these biofilm barriers. This review shows that marine fungi offer promising new alternatives to combat antibiotic-resistant infections, though more research is needed to fully explore their potential.

Impact of Phellinus gilvus mycelia on growth, immunity and fecal microbiota in weaned piglets

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Researchers tested whether a medicinal mushroom called Phellinus gilvus could replace antibiotics in pig feed as a growth promoter. Over 28 days, piglets fed mushroom-supplemented diets grew as well as those given antibiotics while showing even better immune system activation. Unlike antibiotics that drastically changed the gut bacteria composition, the mushroom only slightly modified it while still reducing harmful E. coli bacteria. This suggests the mushroom could be a safer alternative to antibiotics in pig farming.

Research Keyword: antibiotic resistance