Research Keyword: antibiotic resistance

Impact of veterinary pharmaceuticals on environment and their mitigation through microbial bioremediation

Veterinary medicines used in livestock are contaminating our water and soil, creating serious problems like antibiotic-resistant bacteria. Scientists are discovering that natural microorganisms like bacteria and fungi can break down these pharmaceutical pollutants effectively. Advanced technologies combining microbes with electrical systems show promise for cleaning up contaminated wastewater, offering hope for a more sustainable solution to this growing environmental problem.

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CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad-host-range staphylococcal bacteriophage K

Scientists have developed a new method to genetically engineer bacteriophages—viruses that infect bacteria—to fight antibiotic-resistant Staphylococcus aureus infections. Using CRISPR technology, they created a special phage that glows when it infects S. aureus cells, allowing doctors to quickly detect this dangerous pathogen in patient blood samples and other clinical samples. This engineered phage works against most S. aureus strains tested, regardless of their resistance to vancomycin, and could lead to new diagnostic tools and treatments for drug-resistant bacterial infections.

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Cumulative exposure of xenobiotics of emerging concern from agrifood under the One Health approach (XENOBAC4OH)

This research programme examines how harmful chemicals from industry and agriculture accumulate in our food supply and environment. Scientists used a ‘One Health’ approach that considers impacts on humans, animals, and ecosystems together. They tested methods to measure chemical contamination in water and soil, studied how bacteria might break down pollutants, and investigated how different farming practices affect the safety of food crops like tomatoes.

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Microplastics and antibiotic resistance genes as rising threats: Their interaction represents an urgent environmental concern

Tiny plastic particles called microplastics are spreading through our environment and creating a dangerous partnership with antibiotic-resistant bacteria. When these plastics accumulate in soil, water, and even food, they carry bacteria with genes that resist antibiotics, making infections harder to treat. This combined threat to human health can spread through wind, water, and the food chain, requiring urgent action to reduce plastic pollution and antibiotic overuse.

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Streptomyces antarcticus sp. nov., isolated from Horseshoe Island, Antarctica

Scientists discovered a new type of bacteria called Streptomyces antarcticus in Antarctic soil that can survive extreme cold and produce valuable compounds. This bacterium can make antibiotics, cancer-fighting molecules, and other useful substances, making it potentially useful for medicine and industry. The bacteria also has genes to break down pharmaceutical pollutants and adapt to harsh conditions, suggesting applications in cleaning up contaminated environments.

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Editorial: Raising the bar: advancing therapeutic strategies for fighting communicable and noncommunicable diseases

Scientists are developing new ways to fight dangerous infections caused by bacteria, viruses, and drug-resistant pathogens. Recent discoveries include safer uses of existing drugs, better dosing strategies tailored to individual patients, and effective combination therapies that reduce antibiotic resistance. These advances represent important progress in treating serious infectious diseases like COVID-19, tuberculosis, and bacterial infections.

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Comprehensive whole metagenomics analysis uncovers microbial community and resistome variability across anthropogenically contaminated soils in urban and suburban areas of Tamil Nadu, India

Researchers analyzed soil samples from eight polluted locations in India to understand how microbes adapt to heavy metal and chemical contamination. They discovered that contaminated soils harbor many bacteria with antibiotic resistance genes and genes that help them survive toxic metals. The most common resistance mechanism was through special pumps that bacteria use to expel antibiotics. This research highlights how polluted environments become reservoirs of antibiotic-resistant bacteria, emphasizing the need for targeted cleanup strategies to protect human and environmental health.

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Genomic analysis of Acinetobacter baumannii DUEMBL6 reveals diesel bioremediation potential and biosafety concerns

Researchers isolated bacteria from diesel-contaminated soils in Bangladesh that can break down diesel fuel efficiently. The best strain, Acinetobacter baumannii DUEMBL6, degraded about 41% of diesel in laboratory tests through multiple enzymatic pathways. However, this bacteria also carries genes for antibiotic resistance and virulence factors, making it both a promising environmental solution and a potential health risk that requires careful monitoring before field application.

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Exploring the Potential and Evaluating Hydrocarbon Degradation by Novel Antarctic Dietzia and Pusillimonas Isolates From a Pristine Environment

Scientists discovered two types of bacteria living in an Antarctic pond that can break down crude oil and petroleum contamination. These bacteria can survive in very cold conditions and harsh environments. Testing showed they could degrade about 79% of crude oil in laboratory conditions and improved cleanup processes in contaminated soil samples. This research suggests these Antarctic bacteria could be useful tools for cleaning up oil-polluted sites, especially in cold regions of the world.

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Use of Ganoderma lucidum grown on agricultural waste to remove antibiotics from water

Researchers discovered that a type of mushroom called Ganoderma lucidum can help clean water contaminated with antibiotics. When the mushroom is grown on leftover agricultural materials like almond shells and coffee grounds, its root-like structure can remove certain antibiotics from water in just three days. This offers a cheap and sustainable way to address antibiotic pollution that contributes to antibiotic-resistant infections.

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