Research Keyword: antibacterial compounds

Rediscovery of viomellein as an antibacterial compound and identification of its biosynthetic gene cluster in dermatophytes

Researchers discovered that skin-infecting fungi called dermatophytes produce a red pigment called viomellein that kills bacteria. By studying the genes responsible for making viomellein, scientists found that this compound may help dermatophytes establish infections by eliminating competing bacteria on the skin. This discovery could explain how these fungi successfully colonize human skin and may lead to new treatment strategies for stubborn fungal infections.

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First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds

Researchers studied a Korean edible mushroom called Amanita hemibapha subsp. javanica and found it contains compounds that can kill the bacteria Helicobacter pylori, which causes stomach ulcers and gastric cancer. One compound in particular showed strong antibacterial activity, performing even better than some known antibiotics. These findings suggest this mushroom could be a natural source for developing new medicines to treat H. pylori infections and fight antibiotic-resistant strains.

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