alternative splicing

Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

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Scientists studied individual nerve cells in fruit flies that control mating behaviors, comparing males and females at a critical developmental stage. Using advanced sequencing technology, they identified 113 distinct types of nerve cells with shared genes but sex-specific differences in expression. The findings reveal how the same basic neural circuits can be fine-tuned differently in males and females to produce their distinct reproductive behaviors.

Plant–Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity

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Fungi form beneficial partnerships with plant roots, helping plants absorb nutrients and resist stress. A key process called alternative splicing allows cells to make different versions of proteins from the same genes, fine-tuning how plants and fungi cooperate. This review explains how alternative splicing acts like a molecular switch that balances the plant’s immune system with accepting the beneficial fungus, and how understanding this could help farmers grow healthier crops with less chemical fertilizers.

Morphogenesis, starvation, and light responses in a mushroom-forming fungus revealed by long-read sequencing and extensive expression profiling

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Researchers created a detailed genetic instruction manual for a common mushroom species called Coprinopsis cinerea. Using advanced sequencing technology, they identified all the genes and precisely mapped where genes start and stop, what controls them, and how they respond to light and hunger. This improved genetic map reveals how mushrooms form fruiting bodies and survive changing environmental conditions, providing a valuable resource for understanding mushroom biology and improving mushroom cultivation.

Transcriptome Analysis Explored the Differential Genes’ Expression During the Development of the Stropharia rugosoannulata Fruiting Body

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Researchers studied how S. rugosoannulata mushrooms grow and develop by analyzing which genes are active at different stages of fruit body formation. They found that the mushroom’s development relies heavily on glucose and amino acid metabolism, with special genetic processes called alternative splicing playing key roles in maturation. This is the first comprehensive genetic study of this edible mushroom’s development, providing valuable information for improving cultivation techniques and mushroom quality.

ELAV/Hu RNA-binding protein family: key regulators in neurological disorders, cancer, and other diseases

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ELAV/Hu proteins are molecular machines that control how cells read and use genetic instructions. Found mostly in the brain and nervous system, these proteins help manage which genes get turned on or off, which is crucial for proper brain development and function. When these proteins go wrong, they can contribute to serious diseases like Alzheimer’s, Parkinson’s, cancer, and autism, making them promising targets for new treatments.

Plant–Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity

mycolabadmin

Fungi and plants form partnerships that help plants grow better and resist stress, with fungi receiving sugars from plants in return for nutrients from the soil. This review explains how a cellular process called alternative splicing acts like a molecular switch that lets plants accept beneficial fungi while keeping the ability to fight off harmful pathogens. Understanding this balance could help farmers grow healthier crops with less chemical pesticides and fertilizers.

Research Keyword: alternative splicing

Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

Plant–Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity

Morphogenesis, starvation, and light responses in a mushroom-forming fungus revealed by long-read sequencing and extensive expression profiling

Transcriptome Analysis Explored the Differential Genes’ Expression During the Development of the Stropharia rugosoannulata Fruiting Body

ELAV/Hu RNA-binding protein family: key regulators in neurological disorders, cancer, and other diseases

Plant–Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity