Research Keyword: alkaline phosphatase

Synthesis and bioactivity of psilocybin analogues containing a stable carbon–phosphorus bond

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Researchers created new chemical versions of psilocybin (the active compound in magic mushrooms) that cannot be broken down by the body’s natural enzymes in the same way. They tested these new compounds to see if they could help with depression and anxiety by targeting specific brain receptors. The best compound worked well on the intended brain receptors but importantly showed less activity on a heart-related receptor, potentially making it safer than natural psilocybin.

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Psilocybin, an Effective Treatment for Major Depressive Disorder in Adults – A Systematic Review

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Psilocybin, a naturally occurring compound found in certain mushroom species, shows significant promise as a treatment for depression. Clinical studies reviewed in this research found that psilocybin-assisted therapy reduced depressive symptoms in every patient studied, with improvements lasting months after treatment. Unlike traditional antidepressants, psilocybin caused only mild temporary side effects and worked faster, suggesting it could become an important alternative treatment for depression.

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Phosphorus-solubilizing fungi improve growth and P nutrition in sorghum at variable salinity levels

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Researchers discovered five types of salt-tolerant fungi that help plants absorb phosphorus even in salty soils. When these fungi were applied to sorghum plants grown in salt-affected soils, the plants grew better and absorbed more phosphorus. The most effective fungus, Penicillium oxalicum, worked by releasing organic acids and other compounds that made phosphorus more available to plants. This discovery offers a promising natural alternative to chemical fertilizers for farming in salt-affected regions.

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